Title : Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway.

Pub. Date : 1999 Mar 26

PMID : 10085141






1 Functional Relationships(s)
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1 In contrast to PIP2 hydrolysis, PLC-gamma1 tyrosine phosphorylation correlated linearly with the total level of Tyr(P)-EGFR stimulated by either ligand, indicating that the functional deficiency of internal EGFR cannot be attributed to an inability to interact with and phosphorylate signaling proteins. Tyrosine phospholipase C gamma 1 Homo sapiens