Title : Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

Pub. Date : 1999 Mar 16

PMID : 10077621






1 Functional Relationships(s)
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1 An early onset colorectal tumor is heterozygous for the analogous Gly --> Ser mutation in hMSH2, and a second hMSH2 mutation was not found, suggesting that this missense mutation may predispose to cancer via a dominant mutator effect. Glycine mutS homolog 2 Homo sapiens