Title : Caspase-dependent activation of calpain during drug-induced apoptosis.

Pub. Date : 1999 Mar 19

PMID : 10075737






1 Functional Relationships(s)
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1 Pretreatment with the pan-caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk) inhibited PARP cleavage, DNA fragmentation, calpain activation, and Bax cleavage and increased cell survival by 40%. Caspase Inhibitor VI poly(ADP-ribose) polymerase 1 Homo sapiens