Title : The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions.

Pub. Date : 1999 Mar

PMID : 10064574






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 All three fluvastatin metabolites were also formed by recombinant CYP2C9, whereas CYP1A1, CYP2C8, CYP2D6, and CYP3A4 produced only 5-hydroxy-fluvastatin. 5-hydroxy-fluvastatin cytochrome P450 family 1 subfamily A member 1 Homo sapiens