Pub. Date : 1999 Feb
PMID : 10048600
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of these enzymes, CYPs 2D6, 3A4 and 3A5 were found to be the ones capable of metabolising risperidone to 9-hydroxyrisperidone, with activities of 7.5, 0.4 and 0.2 pmol pmol(-1) CYP min(-1), respectively. | Paliperidone Palmitate | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |
| 2 | Furthermore, inducers of CYP can significantly increase the formation of 9-hydroxyrisperidone in rat. | Paliperidone Palmitate | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |