Title : Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, on lactate metabolism and muscle high energy phosphates during endotoxic shock in rats.

Pub. Date : 1999 Feb

PMID : 10030795






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The use of L-canavanine, a selective inhibitor of iNOS, might be more suitable. Canavanine nitric oxide synthase 2 Rattus norvegicus
2 In conclusion, in a rodent model of endotoxinic shock, the continuous infusion of L-canavanine, a selective iNOS inhibitor, improved the systemic hemodynamic parameters and the intracellular bio-energetic patterns estimated by in vivo 31P MRS. To the contrary, the continuous infusion of both constitutive and inducible NOS inhibitor L-NMMA was not followed by the same achievement. Canavanine nitric oxide synthase 2 Rattus norvegicus