Heparitin Sulfate

serpin family C member 1 ; Homo sapiens







75 Article(s)
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1 33176060 Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin-dependent anticoagulant activity. 2021 Feb 1
2 33234593 A quantitative method to detect non-antithrombin-binding 3-O-sulfated units in heparan sulfate. 2021 Jan-Jun 1
3 33794550 Effect of Heparanase and Heparan Sulfate Chains in Hemostasis. 2021 Apr 1
4 33924175 Antithrombin and Its Role in Host Defense and Inflammation. 2021 Apr 20 1
5 34743814 SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate. 2021 Dec 15 1
6 32002903 3D Cell-Culture Models for the Assessment of Anticoagulant and Anti-Inflammatory Properties of Endothelial Cells. 2020 1
7 33146178 Visualizing antithrombin-binding 3-O-sulfated heparan sulfate motifs on cell surfaces. 2020 Nov 19 2
8 29173042 Antithrombin conformational modulation by D-myo-inositol 3,4,5,6-tetrakisphosphate (TMI), a novel scaffold for the development of antithrombotic agents. 2018 Nov 1
9 29999301 Mass Spectrometry Reveals a Multifaceted Role of Glycosaminoglycan Chains in Factor Xa Inactivation by Antithrombin. 2018 Aug 14 1
10 25483839 Dynamic properties of the native free antithrombin from molecular dynamics simulations: computational evidence for solvent- exposed Arg393 side chain. 2015 Sep 1
11 25600805 Heparin cofactor II is degraded by heparan sulfate and dextran sulfate. 2015 Feb 20 1
12 25851619 Selective disruption of heparin and antithrombin-mediated regulation of human factor IX. 2015 Jun 1
13 25921251 High-resolution probing heparan sulfate-antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies. 2015 May 28 5
14 24678194 Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition. 2014 Jan 1
15 23083208 An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence. 2013 Jan 15 1
16 24121110 Sequence, phylogenetic and variant analyses of antithrombin III. 2013 Nov 1 1
17 23152789 On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. 2012 1
18 20685328 Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors. 2010 Nov 1
19 19185514 Differentiation of 3-O-sulfated heparin disaccharide isomers: identification of structural aspects of the heparin CCL2 binding motif. 2009 Apr 1
20 18278163 [Natural and synthetic glycosaminoglycans. Molecular characteristics as the basis of distinct drug profiles]. 2008 Feb 1
21 18669628 Human follicular fluid heparan sulfate contains abundant 3-O-sulfated chains with anticoagulant activity. 2008 Oct 17 1
22 18761723 Heparan sulfates from arteries and veins differ in their antithrombin-mediated anticoagulant activity. 2008 Nov 1
23 19035835 Antiangiogenic forms of antithrombin specifically bind to the anticoagulant heparin sequence. 2008 Dec 23 1
24 16394262 Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. 2006 Jan 1
25 17040907 Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors: evidence for differential binding of antiangiogenic and anticoagulant forms of antithrombin to proangiogenic heparan sulfate domains. 2006 Dec 8 5
26 15652173 Structural characterization of human liver heparan sulfate. 2005 Jan 18 1
27 15878740 Dermatan sulfate is the predominant antithrombotic glycosaminoglycan in vessel walls: implications for a possible physiological function of heparin cofactor II. 2005 Apr 15 2
28 15968398 Expression and function of syndecan-4 in human platelets. 2005 Jun 2
29 16260789 Enzymatic redesigning of biologically active heparan sulfate. 2005 Dec 30 1
30 15060080 Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1. 2004 Jun 11 2
31 12581643 Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity. 2003 Feb 21 1
32 12591924 Deletion of P1 arginine in a novel antithrombin variant (antithrombin London) abolishes inhibitory activity but enhances heparin affinity and is associated with early onset thrombosis. 2003 Apr 18 1
33 12886459 Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors. 2003 Aug 1
34 14575696 Platelet factor 4 neutralizes heparan sulfate-enhanced antithrombin inactivation of factor Xa by preventing interaction(s) of enzyme with polysaccharide. 2003 Nov 7 1
35 12168569 The anti-inflammatory actions of antithrombin--a review. 2002 1
36 12244479 Active conformations of glycosaminoglycans. NMR determination of the conformation of heparin sequences complexed with antithrombin and fibroblast growth factors in solution. 2002 Aug 1
37 11522012 High affinity binding of heparin by necrotic tumour cells neutralises anticoagulant activity--implications for cancer related thromboembolism and heparin therapy. 2001 Aug 1
38 10722716 The effect of a reducing-end extension on pentasaccharide binding by antithrombin. 2000 Mar 24 1
39 10810875 [Endothelial cells and coagulation abnormalities]. 2000 Apr 1
40 11006120 Enzymatic modification of heparan sulfate on a biochip promotes its interaction with antithrombin III. 2000 Sep 16 4
41 10026234 Localization and characterization of antithrombin in human kidneys. 1999 Mar 1
42 10065896 On the control of the plasma contact activation system on human endothelium: comparisons with heparin surface. 1999 Jan 1 4
43 10914239 [Danaparoid sodium for dialysis in heparin-associated thrombocytopenia]. 1999 Mar 1 1
44 11212344 Cell surface heparan sulfate proteoglycans and lipoprotein metabolism. 1999 Nov 30 1
45 9916505 [Autoantibodies to heparin polysaccharides bind to vascular endothelial cells]. 1998 Dec 2
46 9213829 [Effectiveness and tolerability of heparan sulfate in the treatment of superficial thrombophlebitis. Controlled clinical study vs sulodexide]. 1997 Apr 1
47 9251237 Heparan sulphate. 1997 May 1
48 9374919 The coagulation/fibrinolysis balance in systemic sclerosis: evidence for a haematological stress syndrome. 1997 Oct 1
49 9395268 Endothelial-derived nitric oxide preserves anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. 1997 Nov 1
50 8689765 Endothelial cell activation in cutaneous vasculitis. 1996 Jan 2