17alpha-dihydroxyprogesterone

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







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1 31039398 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro. 2019 Jul 1