Paclitaxel

toll like receptor 4 ; Homo sapiens







47 Article(s)
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1 33481008 circGFRA1 affects the sensitivity of triple-negative breast cancer cells to paclitaxel via the miR-361-5p/TLR4 pathway. 2021 Jul 3 3
2 33556340 TLR4/IL-6/IRF1 signaling regulates androgen receptor expression: A potential therapeutic target to overcome taxol resistance in ovarian cancer. 2021 Apr 8
3 34022297 Landscape of toll-like receptors expression in tumor microenvironment of triple negative breast cancer (TNBC): Distinct roles of TLR4 and TLR8. 2021 Aug 5 2
4 34600241 Synthesis of small molecules targeting paclitaxel-induced MyD88 expression in triple-negative breast cancer cell lines. 2021 Nov 1 7
5 32278794 Role of the TLR4-androgen receptor axis and genistein in taxol-resistant ovarian cancer cells. 2020 Jul 6
6 32354736 Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis. 2020 Aug 2
7 32447047 Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling. 2020 Oct 4
8 32628454 Ultrasound-Augmented Phase Transition Nanobubbles for Targeted Treatment of Paclitaxel-Resistant Cancer. 2020 Aug 19 3
9 33370338 The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer. 2020 3
10 30578561 Interleukin-1beta released by microglia initiates the enhanced glutamatergic activity in the spinal dorsal horn during paclitaxel-associated acute pain syndrome. 2019 Mar 3
11 32026322 Blockade of TLR4 using TAK-242 (resatorvid) enhances anti-cancer effects of chemotherapeutic agents: a novel synergistic approach for breast and ovarian cancers. 2019 Dec 2
12 28771725 TLR4 and NFκB signaling is critical for taxol resistance in ovarian carcinoma cells. 2018 Mar 16
13 29486738 Compound A attenuates toll-like receptor 4-mediated paclitaxel resistance in breast cancer and melanoma through suppression of IL-8. 2018 Feb 27 12
14 29531019 Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies. 2018 Jun 1
15 30322956 Choosing the Best Chemotherapy Agent to Boost Immune Checkpoint Inhibition Activity. 2018 Oct 15 1
16 30355931 Effect of Paclitaxel+Hirudin on the TLR4-MyD88 Signaling Pathway During Inflammatory Activation of Human Coronary Artery Smooth Muscle Cells and Mechanistic Analysis. 2018 7
17 28108630 Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. 2017 Mar 1
18 28242239 Role of Toll-like receptor 4 in drug-drug interaction between paclitaxel and irinotecan in vitro. 2017 Jun 6
19 28440494 Low-dose paclitaxel suppresses the induction of M2 macrophages in gastric cancer. 2017 Jun 6
20 26636884 Folate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Copolymer to Overcome TLR4 Driven Chemotherapy Resistance. 2016 Jan 11 3
21 27059733 Galectin-3 induces ovarian cancer cell survival and chemoresistance via TLR4 signaling activation. 2016 Sep 5
22 27262815 PFKFB3 potentially contributes to paclitaxel resistance in breast cancer cells through TLR4 activation by stimulating lactate production. 2016 May 30 2
23 25388329 Activation of TLR-4 to produce tumour necrosis factor-α in neuropathic pain caused by paclitaxel. 2015 Aug 3
24 25681684 Differential activation of NF-κB signaling is associated with platinum and taxane resistance in MyD88 deficient epithelial ovarian cancer cells. 2015 Apr 1
25 25868824 Paclitaxel induces acute pain via directly activating toll like receptor 4. 2015 Mar 11 5
26 25998620 The Role of TLR4 in Chemotherapy-Driven Metastasis. 2015 Jun 15 1
27 26424893 The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4. 2015 Sep 30 8
28 24420921 Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions. 2014 Feb 15 2
29 24452475 Atractylenolide-I sensitizes human ovarian cancer cells to paclitaxel by blocking activation of TLR4/MyD88-dependent pathway. 2014 Jan 23 6
30 24527095 TLR4 induces tumor growth and inhibits paclitaxel activity in MyD88-positive human ovarian carcinoma in vitro. 2014 Mar 5
31 25274031 Paclitaxel therapy promotes breast cancer metastasis in a TLR4-dependent manner. 2014 Oct 1 7
32 25550688 Differential drug resistance acquisition to doxorubicin and paclitaxel in breast cancer cells. 2014 1
33 23720768 TLR4 is a novel determinant of the response to paclitaxel in breast cancer. 2013 Aug 9
34 24371445 Combinations of TLR ligands: a promising approach in cancer immunotherapy. 2013 1
35 22533866 Prognostic significance of MyD88 expression by human epithelial ovarian carcinoma cells. 2012 Apr 25 1
36 22743248 Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway. 2012 Sep 5
37 21091668 Toll-like receptor (TLR)-4 mediates anti-β2GPI/β2GPI-induced tissue factor expression in THP-1 cells. 2011 Feb 1
38 19200169 Role of TLR4 for paclitaxel chemotherapy in human epithelial ovarian cancer cells. 2009 Feb 7
39 19619321 KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells. 2009 Jul 20 1
40 19826413 TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer. 2009 Dec 10 5
41 18650420 Paclitaxel binding to human and murine MD-2. 2008 Oct 10 3
42 18688857 Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel. 2008 Oct 15 4
43 18977229 Taxanes inhibit human TLR4 signaling by binding to MD-2. 2008 Nov 26 1
44 16585214 TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. 2006 Apr 1 1
45 15829295 Differential induction of apoptosis by LPS and taxol in monocytic cells. 2005 May 1
46 12139759 MyD88 is involved in the signalling pathway for Taxol-induced apoptosis and TNF-alpha expression in human myelomonocytic cells. 2002 Aug 1
47 11357875 Toll-like receptors; their physiological role and signal transduction system. 2001 Apr 1