Glucose

sucrase-isomaltase ; Homo sapiens







198 Article(s)
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1 33427491 Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review. 2022 2
2 35040740 Application of starch-based nanoparticles and cyclodextrin for prebiotics delivery and controlled glucose release in the human gut: a review. 2022 Jan 18 2
3 35056861 Anti-α-Glucosidase and Antiglycation Activities of α-Mangostin and New Xanthenone Derivatives: Enzymatic Kinetics and Mechanistic Insights through In Vitro Studies. 2022 Jan 15 1
4 35211990 Research on antioxidant performance of diglucosyl gallic acid and its application in emulsion cosmetics. 2022 Apr 1
5 35397147 Inhibition of α-amylase and α-glucosidase by Morus australis fruit extract and its components iminosugar, anthocyanin, and glucose. 2022 Apr 3
6 35497918 Correlation of Serum IGF-1R, VEGF, and ET Levels with Bone Mineral Density in Type 2 Diabetic Mellitus Patients Treated with Metformin Plus α-Glucosidase Inhibitors. 2022 1
7 31808390 Study on the Interaction of 1,5-diaryl Pyrrole Derivatives with α- glucosidase; Synthesis, Molecular Docking, and Kinetic Study. 2021 2
8 32851964 Novel Coumarin Containing Dithiocarbamate Derivatives as Potent α-Glucosidase Inhibitors for Management of Type 2 Diabetes. 2021 1
9 32926336 PTP1B and α-glucosidase inhibitors from Selaginella rolandi-principis and their glucose uptake stimulation. 2021 Jan 1
10 33092516 Berberine in the Treatment of Diabetes Mellitus: A Review. 2021 1
11 33288319 Celebrex derivatives: Synthesis, α-glucosidase inhibition, crystal structures and molecular docking studies. 2021 Jan 1
12 33449919 The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes. 2021 Mar 1
13 33476922 Comparative study of inhibition mechanisms of structurally different flavonoid compounds on α-glucosidase and synergistic effect with acarbose. 2021 Jun 15 1
14 33658478 Effects of alpha-glucosidase-inhibiting drugs on acute postprandial glucose and insulin responses: a systematic review and meta-analysis. 2021 Mar 3 1
15 33715179 An online target and rapid screening method for α-glucosidase inhibitors based on capillary electrophoresis. 2021 Jun 1
16 33765180 Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis. 2021 Jul 1
17 33946137 Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silico analysis. 2021 May 5 3
18 34065194 Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An In Silico and Biochemical Approach. 2021 May 20 2
19 34124938 Characterization of an α-Glucosidase Enzyme Conserved in Gardnerella spp. Isolated from the Human Vaginal Microbiome. 2021 Aug 9 1
20 34242650 The glucose-regulated protein GRP94 interacts avidly in the endoplasmic reticulum with sucrase-isomaltase isoforms that are associated with congenital sucrase-isomaltase deficiency. 2021 Sep 1 1
21 34411978 Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel α-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation. 2021 Oct 1
22 34439553 Pathophysiological Association between Diabetes Mellitus and Endothelial Dysfunction. 2021 Aug 18 2
23 34527658 Targeting N-Terminal Human Maltase-Glucoamylase to Unravel Possible Inhibitors Using Molecular Docking, Molecular Dynamics Simulations, and Adaptive Steered Molecular Dynamics Simulations. 2021 1
24 34736132 Synthesis and in vitro evaluation of chlorogenic acid amides as potential hypoglycemic agents and their synergistic effect with acarbose. 2021 Dec 1
25 34931981 An Overview of Phytotherapy Used in the Management of Type II Diabetes. 2021 Jun 17 1
26 34944521 In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes. 2021 Dec 14 1
27 31553294 Coumarin-based Scaffold as α-glucosidase Inhibitory Activity: Implication for the Development of Potent Antidiabetic Agents. 2020 1
28 31844870 Emerging strategies for the activity assay and inhibitor screening of alpha-glucosidase. 2020 Jan 29 4
29 32001286 Enzymatically elongated rice starches by amylosucrase from Deinococcus geothermalis lead to slow down the glucose generation rate at the mammalian α-glucosidase level. 2020 Apr 15 1
30 32089234 Seaweed-derived bioactives as potential energy regulators in obesity and type 2 diabetes. 2020 1
31 32194128 Determination of glucose generation rate from various types of glycemic carbohydrates by mammalian glucosidases anchored in the small intestinal tissue. 2020 Jul 1 1
32 32301514 Persimmon highly galloylated-tannins in vitro mitigated α-amylase and α-glucosidase via statically binding with their catalytic-closed sides and altering their secondary structure elements. 2020 Jul 1
33 32802126 Inhibition of Digestive Enzyme and Stimulation of Human Liver Cells (HepG2) Glucose Uptake by Date Seeds Extract. 2020 1
34 32916220 An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications. 2020 Nov 2
35 33024458 Differences in the effects of Kenyan, Tanzanian, and Ethiopian coffee intake on interstitial glucose levels measured by FreeStyle Libre: A pilot case study. 2020 1
36 30599411 Synthesis of benzothiazole derivatives as a potent α-glucosidase inhibitor. 2019 Apr 2
37 30604594 Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. 2019 Jun 1
38 30776576 Polyoxomolybdates as α-glucosidase inhibitors: Kinetic and molecular modeling studies. 2019 Apr 1
39 30954797 Integrated multi-spectroscopic and molecular modelling techniques to probe the interaction mechanism between salvianolic acid A and α‑glucosidase. 2019 Jul 5 1
40 30976294 Fabrication of paper-based enzyme immobilized microarray by 3D-printing technique for screening α-glucosidase inhibitors in mulberry leaves and lotus leaves. 2019 1
41 31019154 Usefulness of antidiabetic alpha-glucosidase inhibitors: a review on the timing of administration and effects on gut hormones. 2019 May 28 1
42 31071387 Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes. 2019 Jul 1
43 31333110 Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update. 2019 1
44 31404793 Synthesis of novel (R)-4-fluorophenyl-1H-1,2,3-triazoles: A new class of α-glucosidase inhibitors. 2019 Oct 1
45 31493868 MiR-26a and miR-26b downregulate the expression of sucrase-isomaltase enzyme: A new chapter in diabetes treatment. 2019 Oct 29 1
46 31593486 Considerations when using alpha-glucosidase inhibitors in the treatment of type 2 diabetes. 2019 Dec 1
47 31672500 Relationship between glucose variability evaluated by continuous glucose monitoring and clinical factors, including glucagon-stimulated insulin secretion in patients with type 2 diabetes. 2019 Dec 1
48 32024621 Alpha-glucosidase inhibition and molecular docking studies of 1,2-benzothiazine 1,1-dioxide based carbohydrazides. 2019 Nov 1
49 28950431 Efficacy and safety of combination therapy with an α-glucosidase inhibitor and a dipeptidyl peptidase-4 inhibitor in patients with type 2 diabetes mellitus: A systematic review with meta-analysis. 2018 Jul 1
50 29421697 A new entry into the portfolio of α-glucosidase inhibitors as potent therapeutics for type 2 diabetes: Design, bioevaluation and one-pot multi-component synthesis of diamine-bridged coumarinyl oxadiazole conjugates. 2018 Apr 1