234 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34417912 | In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK). | 2022 Feb | 1 |
2 | 34634185 | Pharmacokinetic Drug-Drug Interaction Study of Omecamtiv Mecarbil With Amiodarone and Digoxin in Healthy Subjects. | 2022 Mar | 1 |
3 | 34668334 | Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition. | 2022 Jan | 4 |
4 | 34812580 | The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P-Glycoprotein Substrate Digoxin in Healthy Volunteers. | 2022 Jan | 1 |
5 | 34903589 | Transplacental Pharmacokinetic Model of Digoxin Based on Ex Vivo Human Placental Perfusion Study. | 2022 Mar | 3 |
6 | 35118821 | Effect of enzalutamide on PK of P-gp and BCRP substrates in cancer patients: CYP450 induction may not always predict overall effect on transporters. | 2022 May | 2 |
7 | 35163972 | The System Profile of Renal Drug Transporters in Tubulointerstitial Fibrosis Model and Consequent Effect on Pharmacokinetics. | 2022 Jan 21 | 2 |
8 | 35215354 | Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices. | 2022 Feb 18 | 3 |
9 | 35570332 | Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney. | 2022 May 15 | 2 |
10 | 32757312 | Impact of interleukin-6 on drug transporters and permeability in the hCMEC/D3 blood-brain barrier model. | 2021 Apr | 2 |
11 | 32918831 | Evaluation of Potential Drug-Drug Interaction Risk of Pexidartinib With Substrates of Cytochrome P450 and P-Glycoprotein. | 2021 Mar | 1 |
12 | 33532991 | Increasing Intracellular Levels of Iron with Ferric Ammonium Citrate Leads to Reduced P-glycoprotein Expression in Human Immortalised Brain Microvascular Endothelial Cells. | 2021 Jan | 1 |
13 | 33625694 | Awareness and Knowledge Among Internal Medicine House-Staff for Dose Adjustment of Cardiovascular Drugs in Chronic Kidney Disease. | 2021 Mar | 1 |
14 | 33888353 | Evaluating the Risk of Digitalis Intoxication Associated With Concomitant Use of Dronedarone and Digoxin Using Real-World Data. | 2021 May | 1 |
15 | 33962209 | The study of Raddeanin A cerebrovascular endothelial cell trafficking through P-glycoprotein. | 2021 Jun 25 | 1 |
16 | 34268580 | Differences in P-glycoprotein activity in human and rodent blood-brain barrier assessed by mechanistic modelling. | 2021 Sep | 1 |
17 | 34477937 | Impact of fedratinib on the pharmacokinetics of transporter probe substrates using a cocktail approach. | 2021 Dec | 1 |
18 | 32174309 | Corrigendum to "The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure" [Placenta 36 (2015) 1138-1147]. | 2020 Feb | 1 |
19 | 32719417 | Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin. | 2020 Jul 27 | 6 |
20 | 33045114 | Assessment of Clinical Drug-Drug Interactions of Elagolix, a Gonadotropin-Releasing Hormone Receptor Antagonist. | 2020 Dec | 1 |
21 | 33442480 | Multifaceted anti-colorectal tumor effect of digoxin on HCT8 and SW620 cells in vitro. | 2020 Dec | 2 |
22 | 30259783 | Posaconazole-digoxin drug-drug interaction mediated by inhibition of P-glycoprotein. | 2019 Oct | 1 |
23 | 30280663 | Drug-Drug Interactions of P-gp Substrates Unrelated to CYP Metabolism. | 2019 | 7 |
24 | 31269278 | Impact of reduced P-glycoprotein function on digoxin concentrations in patients with dementia. | 2019 Oct | 4 |
25 | 31371422 | Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions. | 2019 Oct | 1 |
26 | 28906558 | Effects of Rolapitant Administered Intravenously or Orally on the Pharmacokinetics of Digoxin (P-glycoprotein Substrate) and Sulfasalazine (Breast Cancer Resistance Protein Substrate) in Healthy Volunteers. | 2018 Feb | 1 |
27 | 29146563 | Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates. | 2018 Jan 15 | 1 |
28 | 29317410 | Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data. | 2018 Mar | 2 |
29 | 29541662 | Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates. | 2018 Feb | 4 |
30 | 29797179 | Use of a Caco-2 permeability assay to evaluate the effects of several Kampo medicines on the drug transporter P-glycoprotein. | 2018 Sep | 1 |
31 | 30022812 | Effect of green tea catechins on the pharmacokinetics of digoxin in humans. | 2018 | 1 |
32 | 30135242 | Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine. | 2018 Nov | 2 |
33 | 27717999 | Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects. | 2017 Jan | 2 |
34 | 27822600 | Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens. | 2017 Jan | 1 |
35 | 27856526 | Extrapolation of Elementary Rate Constants of P-glycoprotein-Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells. | 2017 Feb | 1 |
36 | 28028729 | Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein. | 2017 Mar | 1 |
37 | 28208135 | ABCB1 and SLCO1B3 Gene Polymorphisms and Their Impact on Digoxin Pharmacokinetics in Atrial Fibrillation Patients among the Tunisian Population. | 2017 | 7 |
38 | 28257659 | Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein. | 2017 Mar 15 | 1 |
39 | 28479352 | Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models. | 2017 Sep | 2 |
40 | 26823559 | Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein. | 2016 Jan 28 | 9 |
41 | 26869433 | Usefulness of A Model-Based Approach for Estimating In Vitro P-Glycoprotein Inhibition Potency in a Transcellular Transport Assay. | 2016 Feb | 1 |
42 | 27499787 | Inhibition of P-glycoprotein expression and function by anti-diabetic drugs gliclazide, metformin, and pioglitazone in vitro and in situ. | 2016 May-Jun | 1 |
43 | 27652191 | Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs. | 2016 | 1 |
44 | 25802484 | ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. | 2015 | 1 |
45 | 25932627 | Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport. | 2015 | 1 |
46 | 25940551 | Interindividual epigenetic variation in ABCB1 promoter and its relationship with ABCB1 expression and function in healthy Chinese subjects. | 2015 Nov | 1 |
47 | 25981193 | The Use of Transporter Probe Drug Cocktails for the Assessment of Transporter-Based Drug-Drug Interactions in a Clinical Setting-Proposal of a Four Component Transporter Cocktail. | 2015 Sep | 1 |
48 | 26311557 | The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure. | 2015 Oct | 4 |
49 | 26426900 | Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein. | 2015 | 1 |
50 | 26514315 | Effects of Fostamatinib on the Pharmacokinetics of Digoxin (a P-Glycoprotein Substrate): Results From in Vitro and Phase I Clinical Studies. | 2015 Dec 1 | 2 |