Flavonoids

ATP binding cassette subfamily B member 1 ; Homo sapiens







80 Article(s)
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1 35594703 The influence of green tea extract on nintedanib's bioavailability in patients with pulmonary fibrosis. 2022 Jul 1
2 33570057 Rhamnetin decelerates the elimination and enhances the antitumor effect of the molecular-targeting agent sorafenib in hepatocellular carcinoma cells via the miR-148a/PXR axis. 2021 Mar 21 2
3 33573609 Retraction Note: Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines. 2021 Feb 11 1
4 33735724 A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance. 2021 May 3
5 33808505 Screening of Natural Compounds as P-Glycoprotein Inhibitors against Multidrug Resistance. 2021 Mar 30 1
6 34217736 Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells. 2021 Sep 11
7 32422185 Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter. 2020 Aug 15 1
8 32722234 Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators. 2020 Jul 24 2
9 32816867 The Effects of Traditional Chinese Medicine on P-Glycoprotein-Mediated Multidrug Resistance and Approaches for Studying the Herb-P-Glycoprotein Interactions. 2020 Oct 2
10 30688455 Establishment and Use of Human Mouth Epidermal Carcinoma (KB) Cells Overexpressing P-Glycoprotein To Characterize Structure Requirements for Flavonoids Transported by the Efflux Transporter. 2019 Feb 27 8
11 30790579 Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships. 2019 Apr 15 6
12 30959046 Glabridin resensitizes p-glycoprotein-overexpressing multidrug-resistant cancer cells to conventional chemotherapeutic agents. 2019 Jun 5 1
13 31035631 Quantitative Structure⁻Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells. 2019 Apr 27 4
14 29433224 Structure characteristics for intestinal uptake of flavonoids in Caco-2 cells. 2018 Mar 4
15 30351934 Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry". 2018 Nov 21 1
16 30469543 Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein Function. 2018 Nov 22 1
17 30477461 Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines. 2018 Nov 26 6
18 28028694 A new model of flavonoids affinity towards P-glycoprotein: genetic algorithm-support vector machine with features selected by a modified particle swarm optimization algorithm. 2017 Feb 4
19 28427563 Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals. 2017 1
20 28462502 Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative. 2017 Aug 2
21 28632894 Flavonoids as modulators of metabolic enzymes and drug transporters. 2017 Jun 1
22 26463658 Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia. 2016 Jul 29 1
23 27058921 Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. 2016 Aug 1
24 27216424 Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer. 2016 Jul 19 4
25 27626051 3D-QSAR modelling dataset of bioflavonoids for predicting the potential modulatory effect on P-glycoprotein activity. 2016 Dec 1
26 27652191 Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs. 2016 2
27 26291333 A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo. 2015 Oct 5 3
28 24206113 A genetic algorithm- back propagation artificial neural network model to quantify the affinity of flavonoids toward P-glycoprotein. 2014 Feb 5
29 24362044 Transport of active flavonoids, based on cytotoxicity and lipophilicity: an evaluation using the blood-brain barrier cell and Caco-2 cell models. 2014 Apr 2
30 24613626 Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein. 2014 Apr 1 1
31 24875445 Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux. 2014 Aug 1 1
32 25205494 Molecular docking and P-glycoprotein inhibitory activity of flavonoids. 2014 Sep 5
33 25756670 Molecular factors influencing the affinity of flavonoid compounds on P-glycoprotein efflux transporter. 2014 5
34 22320402 Amine linked flavonoid dimers as modulators for P-glycoprotein-based multidrug resistance: structure-activity relationship and mechanism of modulation. 2012 Mar 8 1
35 21247706 Can flavonoids from honey alter multidrug resistance? 2011 Apr 5
36 21728961 Targeting the multidrug ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation. 2011 1
37 22187677 Interaction of phenothiazines, stilbenes and flavonoids with multidrug resistance-associated transporters, P-glycoprotein and MRP1. 2011 2
38 19897037 Cellular uptake, stability, visualization by 'Naturstoff reagent A', and multidrug resistance protein 1 gene-regulatory activity of cyanidin in human keratinocytes. 2010 Mar 1
39 20487633 Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin- resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy. 2010 Apr-Jun 1
40 20645919 Reversal of multidrug resitance by natural substances from plants. 2010 1
41 20823598 A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport. 2010 Sep 3
42 18955135 A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein. 2009 Feb 15 1
43 19034627 Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. 2009 Apr 1
44 19288491 Flavonoid dimers as bivalent modulators for p-glycoprotein-based multidrug resistance: structure-activity relationships. 2009 Apr 1
45 19323275 Modulation of anticancer drug-induced P-glycoprotein expression by naringin. 2009 Jan-Feb 1
46 19470292 Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. 2009 3
47 19739602 Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. 2009 Sep 1
48 18951251 Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models. 2008 Dec 2
49 17345086 Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: transporter specificity and structure-activity relationship. 2007 Nov 3
50 18261373 Antioxidant and chemosensitizing effects of flavonoids with hydroxy and/or methoxy groups and structure-activity relationship. 2007 4