Reactive Oxygen Species

ATP binding cassette subfamily B member 1 ; Homo sapiens







43 Article(s)
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1 35044379 A self-amplified ROS-responsive chemodrug-inhibitor conjugate for multi-drug resistance tumor therapy. 2022 Feb 15 1
2 32229058 Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells. 2021 Jun 2
3 33532991 Increasing Intracellular Levels of Iron with Ferric Ammonium Citrate Leads to Reduced P-glycoprotein Expression in Human Immortalised Brain Microvascular Endothelial Cells. 2021 Jan 2
4 33658706 Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel. 2021 Dec 1
5 34011375 Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP). 2021 May 19 4
6 34462267 The Interleukin-6/Signal Transducer and Activator of Transcription-3/Cystathionine γ-Lyase Axis Deciphers the Transformation Between the Sensitive and Resistant Phenotypes of Breast Cancer Cells. 2021 Nov 2
7 34751283 Cross-linking of S-nitrosothiolated AIEgens inside cancer cells to monitor NO release and reverse chemo-resistance. 2021 Nov 23 2
8 32037157 Suppression of P-glycoprotein by cigarette smoke extract in human lung-derived A549/P-gp cells. 2020 Apr 2
9 32562941 Porous Pt nanoparticles loaded with doxorubicin to enable synergistic Chemo-/Electrodynamic Therapy. 2020 Oct 2
10 30806880 Exposure of Cultured Astrocytes to Menadione Triggers Rapid Radical Formation, Glutathione Oxidation and Mrp1-Mediated Export of Glutathione Disulfide. 2019 May 1
11 30828537 A pH/ROS Cascade-Responsive Charge-Reversal Nanosystem with Self-Amplified Drug Release for Synergistic Oxidation-Chemotherapy. 2019 Feb 20 2
12 30911326 Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generation. 2019 1
13 30972167 Down-regulation of intracellular reactive oxygen species attenuates P-glycoprotein-associated chemoresistance in Epstein-Barr virus-positive NK/T-cell lymphoma. 2019 4
14 31302132 MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells. 2019 Oct 2
15 31465208 Enhanced Reactive Oxygen Species Generation by Mitochondria Targeting of Anticancer Drug To Overcome Tumor Multidrug Resistance. 2019 Oct 14 2
16 28401939 MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. 2018 Jan 1
17 28881205 Near-infrared triggered co-delivery of doxorubicin and quercetin by using gold nanocages with tetradecanol to maximize anti-tumor effects on MCF-7/ADR cells. 2018 Jan 1 2
18 29305422 Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones. 2018 Mar 9 1
19 29377384 Paris saponin VII induces cell cycle arrest and apoptosis by regulating Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells. 2018 May 1
20 30231924 The effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo. 2018 Sep 19 5
21 28000873 Salvianolic acid B reverses multidrug resistance in HCT‑8/VCR human colorectal cancer cells by increasing ROS levels. 2017 Feb 3
22 28106284 Oxidative Stress Promotes Doxorubicin-Induced Pgp and BCRP Expression in Colon Cancer Cells Under Hypoxic Conditions. 2017 Jul 2
23 28630426 The down-regulation of SLC7A11 enhances ROS induced P-gp over-expression and drug resistance in MCF-7 breast cancer cells. 2017 Jun 19 5
24 29050217 Triterpenoids from Aglaia abbreviata exert cytotoxicity and multidrug resistant reversal effect in MCF-7/ADM cells via reactive oxygen species induction and P-glycoprotein inhibition. 2017 Sep 19 2
25 27524608 Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance. 2016 Sep 22 1
26 27933980 Nanoceria-Mediated Drug Delivery for Targeted Photodynamic Therapy on Drug-Resistant Breast Cancer. 2016 Nov 23 3
27 25714087 Chabamide induces cell cycle arrest and apoptosis by the Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells. 2015 Jun 1
28 26169035 BME, a novel compound of anthraquinone, down regulated P-glycoprotein expression in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells via generation of reactive oxygen species. 2015 Sep 5 2
29 26545779 NOX1 mediates chemoresistance via HIF1α/MDR1 pathway in gallbladder cancer. 2015 Dec 4-11 1
30 24370495 Ursodeoxycholic acid inhibits overexpression of P-glycoprotein induced by doxorubicin in HepG2 cells. 2014 Feb 5 9
31 23560455 Antiproliferative effect of pheophorbide a-mediated photodynamic therapy and its synergistic effect with doxorubicin on multiple drug-resistant uterine sarcoma cell MES-SA/Dx5. 2013 Oct 4
32 23244145 Is the MDR1 C3435T polymorphism responsible for oral mucositis in children with acute lymphoblastic leukemia? 2012 2
33 20858479 C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line. 2010 Dec 15 3
34 19356099 Study of oxidized lipids as endogenous substrates of P-gp (ABCB1). 2008 Dec 1
35 18032928 Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells. 2007 Nov 1
36 15389514 Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species. 2005 Jan 10 2
37 16083877 Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids. 2005 Aug 15 7
38 12514119 Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. 2003 Mar 1
39 11909640 Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors. 2002 Feb 13 1
40 11279018 Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species. 2001 May 18 10
41 10629088 Redox regulation of P-glycoprotein-mediated multidrug resistance in multicellular prostate tumor spheroids. 2000 Jan 15 3
42 10636889 Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. 2000 Jan 21 5
43 1845955 Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance. 1991 Jan 15 1