Heparitin Sulfate

heparanase ; Homo sapiens







201 Article(s)
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1 34693552 Heparanase is a regulator of natural killer cell activation and cytotoxicity. 2022 Jun 1
2 34981584 Structural Insights into Pixatimod (PG545) Inhibition of Heparanase, a Key Enzyme in Cancer and Viral Infections. 2022 Feb 19 3
3 35319225 Heparanase Blockade as a Novel Dual-Targeting Therapy for COVID-19. 2022 Apr 13 2
4 35388870 Synthesis of novel S- and O-disaccharide analogs of heparan sulfate for heparanase inhibition. 2022 May 4 1
5 35563015 Acute T-Cell-Driven Inflammation Requires the Endoglycosidase Heparanase-1 from Multiple Cell Types. 2022 Apr 21 2
6 33185156 Heparanase Inhibitors in Cancer Progression: Recent Advances. 2021 5
7 33587773 Heparanase expression and activity are increased in platelets during clinical sepsis. 2021 May 2
8 33691578 The expression of heparanase in term and preterm human placentas. 2021 Mar 10 1
9 33794550 Effect of Heparanase and Heparan Sulfate Chains in Hemostasis. 2021 Apr 1
10 34107171 Effect of heparanase inhibitor on tissue factor overexpression in platelets and endothelial cells induced by anti-β2-GPI antibodies. 2021 Sep 1
11 34156395 Computational Investigation Identified Potential Chemical Scaffolds for Heparanase as Anticancer Therapeutics. 2021 May 18 2
12 34220822 Helicobacter pylori-Induced Heparanase Promotes H. pylori Colonization and Gastritis. 2021 2
13 34343822 Role of heparanase 2 (Hpa2) in gastric cancer. 2021 Sep 2
14 34461608 Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer. 2021 Aug 30 2
15 34677445 A Marine λ-Oligocarrageenan Inhibits Migratory and Invasive Ability of MDA-MB-231 Human Breast Cancer Cells through Actions on Heparanase Metabolism and MMP-14/MMP-2 Axis. 2021 Sep 28 1
16 34917926 Targeting the "sweet spot" in septic shock - A perspective on the endothelial glycocalyx regulating proteins Heparanase-1 and -2. 2021 Dec 4
17 31518222 New Advances of Heparanase in Human Diseases. 2020 1
18 32222663 Antitumor activity and structure-activity relationship of heparanase inhibitors: Recent advances. 2020 May 1 2
19 32274706 Heparanase - Discovery and Targets. 2020 1
20 32274707 Heparanase: Historical Aspects and Future Perspectives. 2020 5
21 32274709 An Overview of the Structure, Mechanism and Specificity of Human Heparanase. 2020 2
22 32274711 Heparanase: Cloning, Function and Regulation. 2020 1
23 32274717 Involvement of Heparanase in Gastric Cancer Progression and Immunotherapy. 2020 1
24 32274719 Heparanase: A Potential Therapeutic Target in Sarcomas. 2020 1
25 32274731 Impact of Heparanse on Organ Fibrosis. 2020 4
26 32274732 Heparanase in Acute Kidney Injury. 2020 1
27 32274733 Heparanase in Acute Pancreatitis. 2020 4
28 32274736 Heparanase, Heparan Sulfate and Viral Infection. 2020 4
29 32274738 Hpa2 Gene Cloning. 2020 2
30 32289862 Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway. 2020 Apr 4
31 32377957 Circulating heparan sulfate chains and body weight contribute to anti-Xa levels in cancer patients using the prophylactic dose of enoxaparin. 2020 Jul 2
32 32477959 Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells. 2020 1
33 32623935 Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression. 2020 Dec 1
34 32899927 Nuclear Heparanase Regulates Chromatin Remodeling, Gene Expression and PTEN Tumor Suppressor Function. 2020 Sep 6 2
35 32945393 Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis. 2020 Oct 2
36 33256730 Heparanase and the hallmarks of cancer. 2020 Nov 30 1
37 30818840 λ-Carrageenan Oligosaccharides of Distinct Anti-Heparanase and Anticoagulant Activities Inhibit MDA-MB-231 Breast Cancer Cell Migration. 2019 Feb 27 6
38 30922347 Crosstalk between tumor cells and lymphocytes modulates heparanase expression. 2019 Mar 29 4
39 31001480 Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis. 2019 2
40 31032901 Heparanase promotes glioma progression via enhancing CD24 expression. 2019 Sep 15 3
41 31110966 Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression. 2019 1
42 31480068 Serum Heparanase Level Is Decreased in Stable Coronary Artery Disease. 2019 2
43 31481501 Heparanase Accelerates Obesity-Associated Breast Cancer Progression. 2019 Oct 15 1
44 33654855 A Robust, One-step FRET Assay for Human Heparanase. 2019 Sep 5 1
45 29579286 Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications. 2018 Oct 1 1
46 29803826 Heparanase is expressed in adult human osteoarthritic cartilage and drives catabolic responses in primary chondrocytes. 2018 Aug 1
47 30235481 Pro-Angiogenic Effects of Latent Heparanase and Thrombin Receptor-Mediated Pathways-Do They Share a Common Ground in Melanoma Cells? 2018 Oct 4
48 30333909 The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma. 2018 Sep 18 2
49 30487472 Heparanase: A Multitasking Protein Involved in Extracellular Matrix (ECM) Remodeling and Intracellular Events. 2018 Nov 28 4
50 30850186 New Advances of Heparanase and Heparanase-2 in Human Diseases. 2018 Oct 1