Phenobarbital

nuclear receptor subfamily 1, group I, member 3 ; Rattus norvegicus







24 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33473352 Species differences in phenobarbital-mediated UGT gene induction in rat and human liver microtissues. 2021 1
2 34264181 Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). 2021 May 2
3 34743025 Suppression of apoptotic signaling in rat hepatocytes by non-dioxin-like polychlorinated biphenyls depends on the receptors CAR and PXR. 2021 Dec 2
4 29548889 Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats. 2018 May 1 2
5 30090615 Human relevance of rodent liver tumour formation by constitutive androstane receptor (CAR) activators. 2018 Jul 1 3
6 27889497 In vivo effect of borneol on rat hepatic CYP2B expression and activity. 2017 Jan 5 1
7 28520973 Editor's Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes. 2017 Aug 1 2
8 25489928 Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital. 2015 Feb 3 3
9 19920082 Dependence on the microtubule network and 90-kDa heat shock protein of phenobarbital-induced nuclear translocation of the rat constitutive androstane receptor. 2010 Feb 8
10 19958760 Exposure to antiepileptic drugs does not alter the functionality of P-glycoprotein in brain capillary endothelial and kidney cell lines. 2010 Feb 25 1
11 20461738 Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism. 2010 Jul 1
12 20478346 The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems. 2010 Aug 4
13 20547735 Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. 2010 Sep 2
14 20686344 5-aminoimidazole-4-carboxamide-1-beta-ribofuranoside (AICAR) prevents nuclear translocation of constitutive androstane receptor by AMP-activated protein kinase (AMPK) independent manner. 2010 Aug 3
15 18473823 Induction of nuclear receptors and drug resistance in the brain microvascular endothelial cells treated with antiepileptic drugs. 2008 May 2
16 17904175 DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation. 2007 Dec 15 7
17 18023279 PPARalpha-dependent induction of the energy homeostasis-regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: potential role in starvation adaptation. 2007 Dec 11 2
18 15802384 Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. 2005 Jul 1
19 15953603 Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital. 2005 Jul 4 6
20 16153763 CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers. 2005 Dec 15 3
21 12869653 The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. 2003 Aug 3
22 12124310 Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital. 2002 Aug 4
23 11160864 Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers. 2001 Feb 7
24 1239780 Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs. 1975 Sep 1