beta-Lactams

carbonic anhydrase 4 ; Homo sapiens







8 Article(s)
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1 31954879 β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. 2020 Mar 1 8
2 29306206 Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents. 2018 Jan 20 2
3 28254699 β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells. 2017 Apr 21 2
4 26845138 Synthesis of Combretastatin A-4 Analogs and their Biological Activities. 2016 1
5 27805821 Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin. 2016 Nov 23 2
6 23232969 Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro. 2013 Feb 1
7 23564200 Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer. 2013 Jun 3
8 20699436 The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance. 2010 Nov 4