Calcitriol

cytochrome P450, family 24, subfamily a, polypeptide 1 ; Mus musculus







38 Article(s)
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Pub. Year
#Total Relationships
1 33553989 Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism. 2021 Jan 1
2 32165494 The cytochrome P450 enzyme CYP24A1 increases proliferation of mutant KRAS-dependent lung adenocarcinoma independent of its catalytic activity. 2020 May 1 1
3 32319119 Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D3 kinetics for extrapolation from mouse to man: Commentary. 2020 Mar 1
4 32850381 Knockdown of CYP24A1 Aggravates 1α,25(OH)2D3-Inhibited Migration and Invasion of Mouse Ovarian Epithelial Cells by Suppressing EMT. 2020 2
5 33249854 A Naringin- and Icariin-Contained Herbal Formula, Gushukang, Ameliorated Aged Osteoporosis of Aged Mice with High Calcium Intake. 2020 1
6 30553931 Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D3 and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D3. 2019 Apr 4
7 30875566 Preclinical Prevention Trial of Calcitriol: Impact of Stage of Intervention and Duration of Treatment on Oral Carcinogenesis. 2019 Apr 1
8 31439663 A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues. 2019 Sep 27 2
9 31698751 Synergistic Antitumorigenic Activity of Calcitriol with Curcumin or Resveratrol is Mediated by Angiogenesis Inhibition in Triple Negative Breast Cancer Xenografts. 2019 Nov 6 1
10 29771914 Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)2D3. 2018 1
11 29986424 Lithocholic Acid Is a Vitamin D Receptor Ligand That Acts Preferentially in the Ileum. 2018 Jul 6 1
12 28492801 Orthotopic tumorgrafts in nude mice as a model to evaluate calcitriol effects in breast cancer. 2017 Nov 1
13 26586377 Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice. 2016 Feb 2
14 27106018 Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention. 2016 Oct 3
15 25829051 PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation. 2015 Jul 3
16 26148725 FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes. 2015 Sep 1
17 26441239 A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice. 2015 Dec 1
18 24365583 Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol. 2014 Apr 2
19 23505097 Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone. 2013 Sep 1
20 23897575 Comparative effects of 1α-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on transporters and enzymes in fxr(+/+) and fxr(-/-) mice. 2013 Oct 1
21 22179019 Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D(3) action. 2012 Jul 1 1
22 20591973 CYP24A1 inhibition enhances the antitumor activity of calcitriol. 2010 Sep 5
23 17244627 Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. 2007 Mar 23 6
24 17280828 Characterization of Vitamin D insensitive prostate cancer cells. 2007 Mar 1
25 17556365 Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. 2007 Aug 3 1
26 16691293 Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. 2006 Jun 1
27 17237620 Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis. 2006 1
28 15647825 1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts. 2005 Feb 3
29 16148162 Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice. 2005 Sep 15 1
30 12674324 Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: biochemical, histomorphometric, and biomechanical analyses. 2003 Apr 2
31 11437358 Modulation by cAMP of 1alpha,25-dihydroxyvitamin D3 sensitivity of murine erythroleukemia cells. 2001 Jul 15 6
32 10198318 Expression of 25(OH)D3 24-hydroxylase in distal nephron: coordinate regulation by 1,25(OH)2D3 and cAMP or PTH. 1999 Apr 1
33 9792969 Effect of 26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3 on the expression of vitamin-D-responsive genes in vitamin-D-deficient mice. 1998 Dec 2
34 9165006 Mouse vitamin D-24-hydroxylase: molecular cloning, tissue distribution, and transcriptional regulation by 1alpha,25-dihydroxyvitamin D3. 1997 Jun 6
35 7592579 Retinoid X receptor acts as a hormone receptor in vivo to induce a key metabolic enzyme for 1,25-dihydroxyvitamin D3. 1995 Oct 13 2
36 7802698 Induction of vitamin D 24-hydroxylase messenger RNA and activity by 22-oxacalcitriol in mouse kidney and duodenum. Possible role in decrease of plasma 1 alpha,25-dihydroxyvitamin D3. 1994 Nov 29 3
37 2162697 Cultured osteoblasts from normal and hypophosphatemic mice: calcitriol receptors and biological response to the hormone. 1990 1
38 3682815 Regulation of 24-hydroxylase activity in mouse skin fibroblast by cholecalciferol derivatives, triamcinolone acetonide and a calcium modulating agent, nicardipine. 1987 Nov 2