Heparitin Sulfate

coagulation factor II, thrombin ; Homo sapiens







24 Article(s)
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Pub. Year
#Total Relationships
1 33176060 Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin-dependent anticoagulant activity. 2021 Feb 1
2 34743814 SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate. 2021 Dec 15 1
3 29173042 Antithrombin conformational modulation by D-myo-inositol 3,4,5,6-tetrakisphosphate (TMI), a novel scaffold for the development of antithrombotic agents. 2018 Nov 1
4 25483839 Dynamic properties of the native free antithrombin from molecular dynamics simulations: computational evidence for solvent- exposed Arg393 side chain. 2015 Sep 1
5 25600805 Heparin cofactor II is degraded by heparan sulfate and dextran sulfate. 2015 Feb 20 2
6 22577146 Dimerization of matrix metalloproteinase-2 (MMP-2): functional implication in MMP-2 activation. 2012 Jun 29 2
7 23152789 On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. 2012 1
8 21041295 Thrombin-dependent MMP-2 activity is regulated by heparan sulfate. 2010 Dec 31 5
9 16087677 Plasmin- and thrombin-accelerated shedding of syndecan-4 ectodomain generates cleavage sites at Lys(114)-Arg(115) and Lys(129)-Val(130) bonds. 2005 Oct 14 1
10 16107334 Synthesis of anticoagulantly active heparan sulfate proteoglycans by glomerular epithelial cells involves multiple 3-O-sulfotransferase isoforms and a limiting precursor pool. 2005 Nov 11 1
11 10702706 Protein-bound heparin/heparan sulfates in human adult and umbilical cord plasma. 1999 1
12 9526950 Thrombin reduces large heparan sulfate proteoglycan molecules in cultured vascular endothelial cell layers through inhibition of core protein synthesis. 1997 Nov 1 2
13 8603018 Thrombin-mediated activation of endogenous factor XI in plasma in the presence of physiological glycosaminoglycans occurs only with high concentrations of thrombin. 1996 Feb 3
14 8792767 Arterial smooth muscle cell heparan sulfate proteoglycans accelerate thrombin inhibition by heparin cofactor II. 1996 Sep 1
15 8589216 Activation of antithrombin III isoforms by heparan sulphate glycosaminoglycans and other sulphated polysaccharides. 1995 Jul 1
16 8154338 Mechanisms for the anticoagulant effects of synthetic antithrombins. 1993 3
17 8507869 Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrix. 1993 Jun 15 1
18 1612123 Thrombin enhances degradation of heparan sulfate in the extracellular matrix by tumor cell heparanase. 1992 Jul 2
19 1744977 Anticoagulant heparin-like glycosaminoglycans on endothelial cell surface. 1991 Oct 2
20 2529852 Effect of a heparan sulphate with high affinity for antithrombin III upon inactivation of thrombin and coagulation factor Xa. 1989 Sep 1 3
21 2973155 Neutralization of thrombin by antithrombin III in the presence of cultured human fibroblasts. 1988 Jul 15 8
22 3793724 Activation of heparin cofactor II by fibroblasts and vascular smooth muscle cells. 1987 Jan 5 1
23 2436525 Mechanisms for inhibition of the generation of thrombin activity by sulfated polysaccharides. 1986 1
24 6235872 Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways. 1984 Sep 4