Polysaccharides

coagulation factor II, thrombin ; Homo sapiens







43 Article(s)
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1 32594109 Influence of Warfarin Therapy on Prothrombin Production and Its Posttranslational Modifications. 2020 Nov 1 1
2 28282887 New Insights in Thrombin Inhibition Structure-Activity Relationships by Characterization of Octadecasaccharides from Low Molecular Weight Heparin. 2017 Mar 8 1
3 26152729 Intracellular Ascorbate Prevents Endothelial Barrier Permeabilization by Thrombin. 2015 Aug 28 1
4 24561026 Isolation of a pure octadecasaccharide with antithrombin activity from an ultra-low-molecular-weight heparin. 2014 May 15 2
5 18558097 Sulfated galactan is a catalyst of antithrombin-mediated inactivation of alpha-thrombin. 2008 Sep 2
6 17461929 Effect of the anti-factor Xa and anti-factor IIa activities of low-molecular-weight heparins upon the phases of thrombin generation. 2007 May 1
7 16442510 Thrombin inhibition by antithrombin in the presence of oversulfated dermatan sulfates. 2006 Apr 10 1
8 16493483 Modulation of protease nexin-1 activity by polysaccharides. 2006 Feb 3
9 15590773 Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity. 2005 Apr 1
10 12859981 Mechanism of activation of heparin cofactor II by calcium spirulan. 2003 Aug 1 1
11 12948833 Novel approach for preparation of heparins specific to factor Xa using affinity chromatography coupled with synthetic antithrombin III-related peptides. 2003 Jun 1
12 12244069 Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans? 2002 Oct 1
13 12433487 A 2-sulfated, 3-linked alpha-L-galactan is an anticoagulant polysaccharide. 2002 Nov 19 1
14 11816710 Unbalanced effects of dermatan sulfates with different sulfation patterns on coagulation, thrombosis and bleeding. 2001 Nov 1
15 10753952 Activation of heparin cofactor II by calcium spirulan. 2000 Apr 14 2
16 10896248 Proteolytic modulation of thrombopoietin activity: comparison of thrombin, plasmin, and urokinase. 2000 Jun 1
17 9521111 Reactivities of the S2 and S3 subsite residues of thrombin with the native and heparin-induced conformers of antithrombin. 1998 Feb 1
18 9586785 Comparative anticoagulant activity and influence on thrombin generation of dextran derivatives and of a fucoidan fraction. 1998 1
19 9616153 Rapid activation of protein C by factor Xa and thrombin in the presence of polyanionic compounds. 1998 Jun 15 1
20 9657442 Aging and venous thromboembolism influence the pharmacodynamics of the anti-factor Xa and anti-thrombin activities of a low molecular weight heparin (nadroparin). 1998 Jun 1
21 9068899 Mechanism of thrombin inhibition by heparin cofactor II in the presence of dermatan sulphates, native or oversulphated, and a heparin-like dextran derivative. 1997 Feb 2
22 8589216 Activation of antithrombin III isoforms by heparan sulphate glycosaminoglycans and other sulphated polysaccharides. 1995 Jul 1
23 8180343 Defining the heparin-binding domain of antithrombin. 1994 Feb 1
24 1730217 Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082. 1992 Jan 15 1
25 2007588 Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-thrombin reaction. Elucidation from salt concentration effects. 1991 Apr 5 1
26 2226466 Inhibition of factor X and factor V activation by dermatan sulfate and a pentasaccharide with high affinity for antithrombin III in human plasma. 1990 Oct 24 1
27 2236295 Fractionation and characterization of mitogenic and anti-complementary active fractions from kampo (Japanese Herbal) medicine "juzen-taiho-to". 1990 Aug 1
28 2483535 Time-dependent conformational change of thrombin molecules induced by sulfated polysaccharides. 1989 May 4
29 2818566 Anti-thrombin activities of heparin. Effect of saccharide chain length on thrombin inhibition by heparin cofactor II and by antithrombin. 1989 Aug 15 4
30 2443128 The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin. 1987 Apr 15 2
31 3691797 Binding of heparin or dermatan sulfate to thrombin is essential for the sulfated polysaccharide-accelerated inhibition of thrombin by heparin cofactor II. 1987 Dec 10 5
32 2432675 Thrombin inhibitory activity of heparin cofactor II depends on the molecular weight and sulfate amount of dextran sulfate. 1986 Nov 1 1
33 2436525 Mechanisms for inhibition of the generation of thrombin activity by sulfated polysaccharides. 1986 1
34 2411283 The importance of thrombin inhibition for the expression of the anticoagulant activities of heparin, dermatan sulphate, low molecular weight heparin and pentosan polysulphate. 1985 Aug 6
35 6701833 Effect of plasma histidine-rich glycoprotein on the inhibition by anionic polysaccharides of thrombin-triggered platelet aggregation. 1984 Jan 15 1
36 6615439 Properties of antithrombin-thrombin complex formed in the presence and in the absence of heparin. 1983 Aug 1 2
37 6132465 Mechanisms of anticoagulant effects of some sulphated polysaccharides. 1982 Dec 15 1
38 7059522 A novel semi-synthetic sulphated polysaccharide with potent antithrombin activity. 1982 Feb 1
39 6113018 Effect of sulphated polysaccharides on the alpha 1-antitrypsin inhibition of amidolysis catalysed by coagulation cascade proteinases. 1981 Jun 3
40 6159941 Anticoagulant effects of sulphated polysaccharides in normal and antithrombin III-deficient plasmas. 1980 Aug 1
41 7444858 Inhibition of thrombin on surfaces coated with immobilized heparin and heparin-like polysaccharides: a crucial non-thrombogenic principle. 1980 Jul 1-15 1
42 425377 [Determination of fibrinogen concentration in blood plasma by the sulfite precipitation method]. 1979 Jan-Feb 1
43 14387730 The effect of thrombin on the polysaccharide of fibrinogen; a preliminary note. 1955 1