Disulfides

coagulation factor II, thrombin ; Homo sapiens







60 Article(s)
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Title
Pub. Year
#Total Relationships
1 33459316 Barcode signal amplifying strategy for sensitive and accurate protein detection on LC-MS/MS. 2021 Mar 8 1
2 29440720 Structure of prothrombin in the closed form reveals new details on the mechanism of activation. 2018 Feb 13 1
3 27575053 An allosteric disulfide bond is involved in enhanced activation of factor XI by protein disulfide isomerase. 2016 Nov 1
4 22013897 Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase. 2012 Feb 1 2
5 21615106 Protease-resistant peptide ligands from a knottin scaffold library. 2011 Aug 19 1
6 20615204 Design of an in vivo cleavable disulfide linker in recombinant fusion proteins. 2010 Jul 2
7 20981267 Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets. 2010 Oct 11 1
8 18195363 Protection against cerebral malaria by the low-molecular-weight thiol pantethine. 2008 Jan 29 1
9 18209575 Anticoagulant activity of captopril. 2008 Jan 2
10 18424440 Detailed mechanisms of the inactivation of factor VIIIa by activated protein C in the presence of its cofactors, protein S and factor V. 2008 Jun 13 1
11 17059431 Disulfide bond-stabilized factor VIII has prolonged factor VIIIa activity and improved potency in whole blood clotting assays. 2007 Jan 2
12 17490558 [Research progress in hirudin fusion protein--review]. 2007 Feb 2
13 17636263 Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery. 2007 Sep 14 1
14 17681017 Functional role of Bbeta-chain N-terminal fragment in the fibrin polymerization process. 2007 Sep 1
15 15583744 Human platelets contain forms of factor V in disulfide-linkage with multimerin. 2004 Dec 1
16 14499592 Structural stability of human alpha-thrombin studied by disulfide reduction and scrambling. 2003 Sep 23 4
17 14522910 Promotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model. 2003 Sep 15 1
18 12009896 Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond. 2002 May 21 1
19 12192065 Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C. 2002 Sep 1
20 12359097 Platelet-agglutinating protein p37 from a patient with thrombotic thrombocytopenic purpura has characteristics similar to prethrombin 2. 2002 Sep 30 1
21 12434426 Stability of protein-bound conformations of bioactive peptides: the folded conformation of an epidermal growth factor-like thrombomodulin fragment is similar to that recognized by thrombin. 2002 Dec 15 2
22 9882436 Protein disulfide isomerase catalyzes the formation of disulfide-linked complexes of thrombospondin-1 with thrombin-antithrombin III. 1999 Jan 1 1
23 10441134 Protein disulfide isomerase catalyzes the formation of disulfide-linked complexes of vitronectin with thrombin-antithrombin. 1999 Aug 10 3
24 9546612 Characterization of the reciprocal binding sites on human alpha-thrombin and factor XIII A-chain. 1998 Jan 1
25 9636055 Calcium binding properties of an epidermal growth factor-like domain from human thrombomodulin. 1998 Jun 23 1
26 9804847 Endothelial cell VE-cadherin functions as a receptor for the beta15-42 sequence of fibrin. 1998 Nov 13 1
27 9183005 Prothrombin, albumin and immunoglobulin A form covalent complexes with alpha1-microglobulin in human plasma. 1997 May 1 1
28 9232643 The crystal structure of the mouse glandular kallikrein-13 (prorenin converting enzyme). 1997 Jul 1
29 9003757 The 2.8 A crystal structure of Gla-domainless activated protein C. 1996 Dec 16 1
30 7703261 Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs. 1995 Apr 4 1
31 8535250 Thrombin-binding affinities of different disulfide-bonded isomers of the fifth EGF-like domain of thrombomodulin. 1995 Oct 3
32 7947973 The functions of the ninth component of human complement are sustained by disulfide bonds with different susceptibilities to reduction. 1994 Nov 16 1
33 7678252 Ternary vitronectin-thrombin-antithrombin III complexes in human plasma. Detection and mode of association. 1993 Jan 15 1
34 1444441 Reactions of thrombin-serpin complexes with thrombospondin. 1992 Nov 15 7
35 1569180 Cysteamine enhances the procoagulant activity of Factor VIII-East Hartford, a dysfunctional protein due to a light chain thrombin cleavage site mutation (arginine-1689 to cysteine). 1992 May 1
36 1751488 Reconstitution of catalytically competent human zeta-thrombin by combination of zeta-thrombin residues A1-36 and B1-148 and an Escherichia coli expressed polypeptide corresponding to zeta-thrombin residues B149-259. 1991 Dec 17 1
37 2334711 Disulfide bond reduction in fibrinogen: calcium protection and effect on clottability. 1990 Feb 13 1
38 2466666 Monoclonal antibodies against antithrombin III. Identification of their epitopes and effects on antithrombin III activities. 1989 Mar 15 1
39 2482065 Conformational lability of vitronectin: induction of an antigenic change by alpha-thrombin-serpin complexes and by proteolytically modified thrombin. 1989 Sep 19 1
40 2561638 Selective inhibition of thrombin- and plasmin-induced platelet aggregation by a synthetic peptide disulfide. 1989 2
41 2653312 Modification of protein stability by introduction of disulfide bridges and prolines: geometric criteria for mutation sites. 1989 Apr 14 1
42 2758067 [Enzymatic properties of the isolated B-chain of human thrombin]. 1989 Apr 1
43 2781534 On the location in the thrombin B chain of substrate recognition sites for fibrinopeptide release and factor XIII activation. 1989 Sep 15 1
44 2458152 Conformational states of vitronectin: preferential expression of an antigenic epitope when vitronectin is covalently and noncovalently complexed with thrombin-antithrombin III or treated with urea. 1988 Sep 1
45 3179320 Design, synthesis and antithrombin activity for conformationally restricted analogs of peptide anticoagulants based on the C-terminal region of the leech peptide, hirudin. 1988 Nov 2 1
46 3196704 Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition. 1988 Sep 6 1
47 2436912 Inhibition of human vitamin-K-dependent protein-S-cofactor activity by a monoclonal antibody specific for a Ca2+-dependent epitope. 1987 May 15 1
48 3101765 Human neutrophil elastase alters human alpha-thrombin function: limited proteolysis near the gamma-cleavage site results in decreased fibrinogen clotting and platelet-stimulatory activity. 1987 Mar 1
49 2877688 Thrombospondin is a substrate for blood coagulation factor XIIIa. 1986 Sep 23 2
50 3778971 [Effect of reduction of the interchain disulfide bridge of human thrombin on its enzymatic activity and structure]. 1986 Oct 2