Thalidomide

tumor necrosis factor ; Homo sapiens







261 Article(s)
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Pub. Year
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1 33249990 A drug repositioning success: The repositioned therapeutic applications and mechanisms of action of thalidomide. 2021 Apr 1
2 33517358 Repurposing approved drugs for cancer therapy. 2021 Mar 25 2
3 34512420 TNF-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of PTSD and Comorbid Pain. 2021 4
4 32935774 Rationale use of Thalidomide in erythema nodosum leprosum - A non-systematic critical analysis of published case reports. 2020 2
5 30362282 Shedding light on IRIS: from Pathophysiology to Treatment of Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome in HIV-Infected Individuals. 2019 Jan 2
6 30736806 TNF-α/STAT3 pathway epigenetically upregulates Nav1.6 expression in DRG and contributes to neuropathic pain induced by L5-VRT. 2019 Feb 8 1
7 31464258 Thalidomide-induced bronchiolitis obliterans organizing pneumonia in a patient with multiple myeloma. 2019 Jul-Aug 1
8 31819606 Systemic Injection of Thalidomide Prevent and Attenuate Neuropathic Pain and Alleviate Neuroinflammatory Response in the Spinal Dorsal Horn. 2019 1
9 31867326 Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments. 2019 2
10 29719394 Preparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer. 2018 4
11 29732020 Salivary levels of TNF-α in patients with recurrent aphthous stomatitis: A cross-sectional study. 2018 Winter 2
12 29854627 Neuro- and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor suppressor protein p53, neurotransmitters, oxidative stress and histology. 2018 1
13 30301277 Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents. 2018 Oct 7 1
14 28099781 Old Drug Scaffold, New Activity: Thalidomide-Correlated Compounds Exert Different Effects on Breast Cancer Cell Growth and Progression. 2017 Mar 7 1
15 28571559 A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma. 2017 2
16 26440459 LASSBio-1425, an analog of thalidomide, decreases triglyceride and increases HDL cholesterol levels by inhibition of TNF-α production. 2016 Jan 1 1
17 26820153 Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats. 2016 1
18 26951036 Treatment of refractory ulcerative necrobiosis lipoidica diabeticorum with oral thalidomide. 2016 Jan-Feb 1
19 27003992 Effective treatment of gastrointestinal bleeding with thalidomide--Chances and limitations. 2016 Mar 21 1
20 27492707 The molecular mechanism of thalidomide analogs in hematologic malignancies. 2016 Dec 1
21 27556927 Expression of CD64 on Circulating Neutrophils Favoring Systemic Inflammatory Status in Erythema Nodosum Leprosum. 2016 Aug 1
22 25222109 Possible roles of tumor necrosis factor-α and angiotensin II type 1 receptor on high glucose-induced damage in renal proximal tubular cells. 2015 Feb 1
23 25617013 Review of thalidomide use in the pediatric population. 2015 Apr 2
24 25741973 Clinicoradiologic response of neurologic tuberculous mass lesions in children treated with thalidomide. 2015 Feb 1
25 26220057 Prolonged Suppression of Neuropathic Pain by Sequential Delivery of Lidocaine and Thalidomide Drugs Using PEGylated Graphene Oxide. 2015 Nov 1
26 26398114 Therapeutic potential of thalidomide for gemcitabine-resistant bladder cancer. 2015 Nov 2
27 26486925 TNF-alpha antagonists and thalidomide for the management of gastrointestinal Behçet's syndrome refractory to the conventional treatment modalities: a case series and review of the literature. 2015 Nov-Dec 1
28 24134145 Rare atypical presentations in Type 2 lepra reaction: a case series. 2014 Mar 1
29 24275522 Autism's cancer connection: the anti-proliferation hypothesis and why it may matter. 2014 Jan 2
30 24596000 Thalidomide regulation of NF-κB proteins limits Tregs activity in chronic lymphocytic leukemia. 2014 Jan-Feb 2
31 24667589 Mucosal healing with thalidomide in refractory Crohn's disease patients intolerant of anti-TNF-α drugs: report of 3 cases and literature review. 2014 Jul 3
32 24859059 In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs. 2014 Aug 1
33 25531359 Role of immunosuppressives in special situations: perianal disease and postoperative period. 2014 1
34 22710762 Thalidomide has anti-inflammatory properties in neonatal immune cells. 2013 Feb 1
35 23261764 The up-regulation of IL-6 in DRG and spinal dorsal horn contributes to neuropathic pain following L5 ventral root transection. 2013 Mar 1
36 23583898 Thalidomide attenuates excessive inflammation without interrupting lipopolysaccharide-driven inflammatory cytokine production in chronic granulomatous disease. 2013 May 1
37 23717811 The combination of novel targeted molecular agents and radiation in the treatment of pediatric gliomas. 2013 1
38 24284039 Thalidomide distinctly affected TNF-α, IL-6 and MMP secretion by an ovarian cancer cell line (SKOV-3) and primary ovarian cancer cells. 2013 Jul-Sep 4
39 21681114 Thalidomide use and outcomes in pediatric patients with Crohn disease refractory to infliximab and adalimumab. 2012 Jan 1
40 21883476 Genetic variations in multiple myeloma II: association with effect of treatment. 2012 Feb 1
41 22277195 TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation. 2012 Jan 25 1
42 22488443 Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation. 2012 Jun 1
43 22650376 Thalidomide: chemistry, therapeutic potential and oxidative stress induced teratogenicity. 2012 2
44 22650377 TNF α signaling beholds thalidomide saga: a review of mechanistic role of TNF-α signaling under thalidomide. 2012 15
45 22731394 3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit. 2012 Sep 1
46 22880820 The role of thalidomide and placebo for the treatment of cancer-related anorexia-cachexia symptoms: results of a double-blind placebo-controlled randomized study. 2012 Oct 1
47 21215621 Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors. 2011 Feb 1 3
48 21465313 t(11;18)(q21;q21) translocation as predictive marker for non-responsiveness to salvage thalidomide therapy in patients with marginal zone B-cell lymphoma with gastric involvement. 2011 Dec 1
49 21511336 Effects of thalidomide on long-term bone marrow cultures from patients with myelodysplastic syndromes: induction of IL-10 expression in the stromal layers. 2011 Aug 1
50 21792375 Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation. 2011 4