Lipid A

tumor necrosis factor ; Homo sapiens







34 Article(s)
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1 22025552 Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation. 2011 Dec 1 1
2 19531474 Natural phosphoryl and acyl variants of lipid A from Neisseria meningitidis strain 89I differentially induce tumor necrosis factor-alpha in human monocytes. 2009 Aug 7 1
3 18283493 Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists. 2008 Dec 1
4 18440300 Physico-chemical and biophysical study of the interaction of hexa- and heptaacyl lipid A from Erwinia carotovora with magainin 2-derived antimicrobial peptides. 2008 Oct 1
5 18826950 Constitutive activation of phosphatidylinositol 3-kinase signaling pathway down-regulates TLR4-mediated tumor necrosis factor-alpha release in alveolar macrophages from asymptomatic HIV-positive persons in vitro. 2008 Nov 28 1
6 18827361 The preparation of a lipidic endotoxin affects its biological activities. 2008 Oct 1
7 17513113 The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A. 2007 Jul 15 1
8 16725239 A combination of E. coli DNA fragments and modified lipopolysaccharides as a cancer immunotherapy. 2006 Jul 26 2
9 16109884 HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro. 2005 Dec 2
10 12117916 Modification of the structure and activity of lipid A in Yersinia pestis lipopolysaccharide by growth temperature. 2002 Aug 1
11 12542852 Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application. 2002 1
12 11133766 The interaction of human peripheral blood eosinophils with bacterial lipopolysaccharide is CD14 dependent. 2001 Jan 1 1
13 10690516 Phase I study of ONO-4007, a synthetic analogue of the lipid A moiety of bacterial lipopolysaccharide. 2000 Feb 1
14 10706705 Salmonella-type heptaacylated lipid A is inactive and acts as an antagonist of lipopolysaccharide action on human line cells. 2000 Mar 15 2
15 11083772 Interaction of surfactant protein A with lipopolysaccharide and regulation of inflammatory cytokines in the THP-1 monocytic cell line. 2000 Dec 4
16 11521054 Induction of TNF-alpha and MnSOD by endotoxin: effect of E5531, a synthetic non-toxic lipid A analog. 2000 2
17 10569739 Activity of monosaccharide lipid A analogues in human monocytic cells as agonists or antagonists of bacterial lipopolysaccharide. 1999 Dec 1
18 9435177 ONO-4007, an antitumor lipid A analog, induces tumor necrosis factor-alpha production by human monocytes only under primed state: different effects of ONO-4007 and lipopolysaccharide on cytokine production. 1998 Jan 3
19 9412657 Antitumor effect of DT-5461, a lipid A derivative, against human tumor xenografts is mediated by intratumoral production of tumor necrosis factor and affected by host immunosuppressive factors in nude mice. 1997 1
20 8830332 Effects of a new synthetic lipid A on endogenous tumor necrosis factor production and antitumor activity against human pancreatic cancer cells. 1996 Apr 3
21 8001393 Pretreatment of normal humans with monophosphoryl lipid A induces tolerance to endotoxin: a prospective, double-blind, randomized, controlled trial. 1995 Jan 1
22 7525728 Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway. 1994 Dec 1 2
23 7831357 A case for an endotoxic conformation. 1994 2
24 8119492 Bacterial endotoxin: molecular relationships of structure to activity and function. 1994 Feb 3
25 7687236 The potentiating effect of LPS on tumor necrosis factor-alpha production by influenza A virus-infected macrophages. 1993 Apr 1
26 8225388 Inhibitor of C1q secretion suppresses the macrophage response to lipid A for nitric oxide but not for TNF production: evidence for a role of C1q in autocrine binding of TNF. 1993 Jul 5
27 1508144 [Effect of lipid A on the production of tumor necrosis factor (TNF) and antitumor activity against pancreatic cancer cells: preliminary report]. 1992 Jul 2
28 1547025 Modulation of lipopolysaccharide-induced production of tumor necrosis factor, interleukin 1, and interleukin 6 by synthetic precursor Ia of lipid A. 1992 Jan 3
29 1576244 Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells. 1992 Feb 5
30 1681579 University of California/Davis Interdepartmental Conference on gram-negative septicemia. 1991 Jul-Aug 1
31 2193101 Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo. 1990 Jul 1 4
32 2613271 Induction of tumor necrosis factor-alpha release by lipopolysaccharide and defined lipopolysaccharide partial structures. 1989 Oct 2
33 2731990 Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins. 1989 Jul 1
34 6528335 Role of lipid A in the production of tumor necrosis factor and differences in antitumor activity between tumor necrosis factor and lipopolysaccharide. 1984 Dec 4