Lysine

tumor necrosis factor ; Homo sapiens







53 Article(s)
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Title
Pub. Year
#Total Relationships
1 34988909 Emergence of clone with PHF6 nonsense mutation in chronic myelomonocytic leukemia at relapse after allogeneic HCT. 2022 May 1
2 35629898 A Review of Metabolomic Profiling in Rheumatoid Arthritis: Bringing New Insights in Disease Pathogenesis, Treatment and Comorbidities. 2022 Apr 27 1
3 29987742 The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells. 2019 Mar 1
4 30659183 Malonylation of GAPDH is an inflammatory signal in macrophages. 2019 Jan 18 1
5 30867746 Inflammatory cytokine-induced expression of MASTL is involved in hepatocarcinogenesis by regulating cell cycle progression. 2019 Mar 1
6 31039328 Inflammation-mediated deacetylation of the ribonuclease 1 promoter via histone deacetylase 2 in endothelial cells. 2019 Aug 1
7 29954944 Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4. 2018 Aug 24 1
8 30361438 Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFα-induced apoptosis. 2018 Dec 28 2
9 28511912 Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction. 2017 Jul 1
10 28794503 Inflammatory genes TNFα and IL6 display no signs of increased H3K4me3 in circulating monocytes from untreated rheumatoid arthritis patients. 2017 Sep 1
11 28958848 SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. 2017 Oct 15 1
12 27079798 Lysine fatty acylation promotes lysosomal targeting of TNF-α. 2016 Apr 15 4
13 25056949 Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis. 2014 Sep 5 1
14 22069318 Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli. 2012 Jan 2 1
15 22184250 Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α-induced JNK activation and inflammation. 2012 Jan 3 2
16 22249179 New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor. 2012 Mar 2 1
17 22406003 Lys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFα-induced NF-κB activation via mediating TAK1 degradation. 2012 Jul 7
18 22995936 KAP1/TRIM28: an inhibitor of IRF5 function in inflammatory macrophages. 2012 Dec 1
19 23075766 SIRT1 regulates CD40 expression induced by TNF-α via NF-ĸB pathway in endothelial cells. 2012 1
20 23285694 Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. 2012 Nov-Dec 1
21 21131586 MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation. 2011 Feb 24 2
22 21151599 Evidence supporting a role for N-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy. 2010 Dec 2 1
23 19586614 Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6. 2009 Nov 2
24 20064471 A model of partnership co-opted by the homeodomain protein TGIF and the Itch/AIP4 ubiquitin ligase for effective execution of TNF-alpha cytotoxicity. 2009 Dec 25 2
25 18439917 Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1. 2008 Aug 2
26 18809684 G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance. 2008 Nov 21 1
27 17306544 Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling. 2007 Mar 6 2
28 17449468 RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. 2007 Jun 8 1
29 17561456 Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants. 2007 Aug 2
30 17646159 Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance. 2007 Sep 14 2
31 16603398 Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. 2006 Apr 21 1
32 16923618 A mutated human tumor necrosis factor-alpha improves the therapeutic index in vitro and in vivo. 2006 2
33 16936264 JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha. 2006 Sep 1
34 17055289 Computation of non-covalent interactions in TNF proteins and interleukins. 2006 Sep 2
35 15664665 Bradykinin upregulates IL-8 production in human gingival fibroblasts stimulated by interleukin-1beta and tumor necrosis factor alpha. 2005 Mar 30 1
36 15972682 beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation. 2005 Jul 1 1
37 16222728 Synthesis and proinflammatory properties of muramyl tripeptides containing lysine and diaminopimelic acid moieties. 2005 Nov 1
38 16422104 [Building immune microsphere against tumor necrosis factor-alpha (TNF-alpha)]. 2005 Dec 1
39 14976218 In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. 2004 Apr 23 4
40 14985084 Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency. 2004 Mar 19 1
41 15027030 Synthesis and receptor binding of IgG1 peptides derived from the IgG Fc region. 2004 Mar-Apr 1
42 15297722 [Creation of functional muteins using phage libraries for pharmacoproteomic-based drug discovery and development of DDS]. 2004 Aug 5
43 15623605 Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window. 2004 Dec 15 1
44 12591926 Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2). 2003 Apr 25 1
45 12665803 Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity. 2003 May 5
46 14616797 Involvement of Fcgamma receptors and beta2 integrins in neutrophil activation by anti-proteinase-3 or anti-myeloperoxidase antibodies. 2003 Nov 1
47 12485916 Triamcinolone acetonide and dexamethasome suppress TNF-alpha-induced histone H4 acetylation on lysine residues 8 and 12 in mononuclear cells. 2002 Nov 1
48 10198233 Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha. 1999 Apr 13 5
49 8577707 Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation. 1996 Feb 6 1
50 8957067 In vivo anti-tumor efficacy of polyethylene glycol-modified tumor necrosis factor-alpha against tumor necrosis factor-resistant tumors. 1996 Oct 4