aloxistatin

cathepsin B ; Homo sapiens







9 Article(s)
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Pub. Year
#Total Relationships
1 28502922 Design, Synthesis, and Structure-Activity Relationship Study of Epoxysuccinyl-Peptide Derivatives as Cathepsin B Inhibitors. 2017 Aug 1 1
2 26388830 Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate. 2015 1
3 24595198 Brain pyroglutamate amyloid-β is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic. 2014 1
4 21613740 The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity. 2011 1
5 22046434 Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals. 2011 1
6 16339296 Zymogen activation in a reconstituted pancreatic acinar cell system. 2006 May 1
7 11776436 L-2,5-dihydrophenylalanine, an inducer of cathepsin-dependent apoptosis in human promyelocytic leukemia cells (HL-60). 2001 Oct 1
8 10098844 Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins Abeta1-40 and Abeta1-42, respectively. 1999 Apr 1
9 9742009 Cysteine protease inhibitor, E-64d, prevents in vitro cerulein- induced trypsinogen activation. 1998 Sep 1