Cysteine

⇄

cathepsin B ; Homo sapiens







42 Article(s)
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Pub. Year
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1 31683457 Differences in cysteine peptidases-like activity in sera of patients with breast cancer. 2020 1
2 32637952 Assessment of Proton-Coupled Conformational Dynamics of SARS and MERS Coronavirus Papain-like Proteases: Implication for Designing Broad-Spectrum Antiviral Inhibitors. 2020 Jul 1 1
3 32962355 Assessment of proton-coupled conformational dynamics of SARS and MERS coronavirus papain-like proteases: Implication for designing broad-spectrum antiviral inhibitors. 2020 Sep 21 1
4 31659177 Antimalarial Quinoline Drugs Inhibit β-Hematin and Increase Free Hemin Catalyzing Peroxidative Reactions and Inhibition of Cysteine Proteases. 2019 Oct 28 1
5 31815017 The Role of Cathepsin B in Peritoneal Fibrosis due to Peritoneal Dialysis. 2019 1
6 31824841 Expression and Clinical Implications of Cysteine Cathepsins in Gallbladder Carcinoma. 2019 2
7 28383558 Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation. 2017 Apr 6 1
8 27902765 Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins. 2016 1
9 25747438 In silico identification of irreversible cathepsin B inhibitors as anti- cancer agents: virtual screening, covalent docking analysis and molecular dynamics simulations. 2015 1
10 24412851 Design, synthesis and docking studies of bischalcones based quinazoline-2(1H)-ones and quinazoline-2(1H)-thiones derivatives as novel inhibitors of cathepsin B and cathepsin H. 2014 Apr 11 1
11 24881000 Theoretical insight into the mechanism for the inhibition of the cysteine protease cathepsin B by 1,2,4-thiadiazole derivatives. 2014 Jun 1
12 24940640 Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins. 2014 Jul 24 2
13 25070180 Screening and identification of small molecule inhibitors of ErbB2-induced invasion. 2014 Dec 1
14 23301676 Novel bis-C,N-cyclometalated iridium(III) thiosemicarbazide antitumor complexes: interactions with human serum albumin and DNA, and inhibition of cathepsin B. 2013 Jan 18 1
15 24204192 Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. 2013 Oct 2
16 21835049 Cathepsin B trafficking in thyroid carcinoma cells. 2011 Aug 3 1
17 20467693 Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT. 2010 Jun 21 1
18 20538006 The occluding loop of cathepsin B prevents its effective inhibition by human kininogens. 2010 Jul 30 1
19 20860624 Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft. 2010 Oct 2
20 19131246 Development of dual-acting prodrugs for circumventing multidrug resistance. 2009 Feb 1 1
21 19199576 Development of protein-binding bifunctional linkers for a new generation of dual-acting prodrugs. 2009 Feb 1
22 17985332 Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer. 2008 Feb 1
23 17656088 Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays. 2007 Sep 1 1
24 16530514 Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation. 2006 Mar 1
25 15853627 Medicinal chemistry and properties of 1,2,4-thiadiazoles. 2005 Apr 1
26 12088202 Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. 2002 1
27 12437106 Cathepsin B stability, but not activity, is affected in cysteine:cystine redox buffers. 2002 Jul-Aug 4
28 11170462 TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells. 2001 Feb 6 1
29 11741472 Identification of dipeptidyl nitriles as potent and selective inhibitors of cathepsin B through structure-based drug design. 2001 Dec 20 1
30 11865974 Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids. 2001 1
31 10869547 The active-site residue Cys-29 is responsible for the neutral-pH inactivation and the refolding barrier of human cathepsin B. 2000 Jun 23 2
32 10384960 Regulation of cathepsin B activity by cysteine and related thiols. 1999 May 9
33 9473776 Cathepsin B, thiols and cysteine protease inhibitors in squamous-cell lung cancer. 1997 4
34 8645703 Cathepsin B activity in normal human osteoblast-like cells and human osteoblastic osteosarcoma cells (MG-63): regulation by interleukin-1 beta and parathyroid hormone. 1996 May 21 1
35 8809301 A comparison of cysteine and serine proteinases in human gingival crevicular fluid with tissue, saliva and bacterial enzymes by analytical isoelectric focusing. 1996 May 1
36 1718025 T-helper-cell determinants in protein antigens are preferentially located in cysteine-rich antigen segments resistant to proteolytic cleavage by cathepsin B, L, and D. 1991 Oct 1
37 2039451 A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses. 1991 May 1 1
38 2385265 Molecular cloning and primary sequence of a cysteine protease expressed by Haemonchus contortus adult worms. 1990 Jun 1
39 2934623 Cytochemical investigation of cathepsin B in rheumatoid synovial membrane and fluid. 1985 Oct-Dec 1
40 6501297 Identity of acyl group conformations in the active sites of papain and cathepsin B by resonance Raman spectroscopy. 1984 Dec 10 1
41 7160384 The slow, tight-binding inhibition of cathepsin B by leupeptin. A hysteretic effect. 1982 Dec 1
42 684867 [Cathepsin B1 activity in cat brain tissue]. 1978 Jul-Aug 1