Cholesterol

cytochrome P450 family 7 subfamily A member 1 ; Homo sapiens







168 Article(s)
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1 34546511 Association of cholesterol 7α-hydroxylase (CYP7A1) promoter polymorphism (rs3808607) and cholesterol 24S-hydroxylase (CYP46A1) intron 2 polymorphism (rs754203) with serum lipids, vitamin D levels, and multiple sclerosis risk in the Turkish population. 2022 Apr 4
2 35210819 Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia. 2022 1
3 35287950 MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1. 2022 May 6
4 35397875 Role of microRNA-185 in the FoxO1-CYP7A1 mediated regulation of bile acid and cholesterol metabolism: A novel target for drug discovery? 2022 May 1
5 33298707 Unique Variant of Cerebrotendinous Xanthomatosis Presenting With Eyelid Involvement Due to Heterozygous CYP7A1 and SLC10A1 Gene Mutations. 2021 Apr 1 1
6 33645254 Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women. 2021 May 1 2
7 33671529 Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence. 2021 Feb 22 1
8 33686046 Atorvastatin Induces FXR and CYP7A1 Activation as a Result of the Sequential Action of PPARγ/PGC-1α/HNF-4α in Hep3B Cells. 2021 Mar 25 1
9 33799730 CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Are Associated with Increased Serum Coenzyme Q10 after Long-Term Supplementation in Women. 2021 Mar 11 1
10 34845882 The association of cytochrome 7A1 and ATP-binding cassette G8 genotypes with type 2 diabetes among Jordanian patients. 2021 Nov 29 2
11 34925816 Lactobacillus mediates the expression of NPC1L1, CYP7A1, and ABCG5 genes to regulate cholesterol. 2021 Dec 2
12 31724712 miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish. 2020 Mar 1 1
13 32018318 [What the (abdominal) surgeon needs to know on novel insights regarding cholic acids and their interaction with the intestinal microbioma]. 2020 Mar 4
14 32035489 Ezetimibe promotes CYP7A1 and modulates PPARs as a compensatory mechanism in LDL receptor-deficient hamsters. 2020 Feb 8 2
15 32241558 Transthyretin Regulated by linc00657/miR-205-5p Promoted Cholesterol Metabolism by Inducing SREBP2-HMGCR and Inhibiting LXRα-CYP7A1. 2020 May 1
16 32253466 Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma cells. 2020 May 1
17 32591337 The lipid transfer properties of CETP define the concentration and composition of plasma lipoproteins. 2020 Aug 1
18 32674250 Response of serum LDL cholesterol to oatmeal consumption depends on CYP7A1_rs3808607 genotype in Chinese. 2020 4
19 33135418 A Membrane-free Liver-Gut-on-Chip Platform for the Assessment on Dysregulated Mechanisms of Cholesterol and Bile Acid Metabolism Induced by PM2.5. 2020 Nov 25 1
20 30503707 Lipoprotein-X fifty years after its original discovery. 2019 Jan 1
21 30529590 Rosuvastatin improves the FGF19 analogue NGM282-associated lipid changes in patients with non-alcoholic steatohepatitis. 2019 Apr 2
22 30554802 PPARγ overexpression regulates cholesterol metabolism in human L02 hepatocytes. 2019 Jan 1
23 30709899 Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid. 2019 Apr 3
24 30978324 Advances in understanding the regulatory mechanism of cholesterol 7α-hydroxylase. 2019 Jun 1
25 31413246 Is Plant Sterols a Good Strategy to Lower Cholesterol? 2019 Sep 4 1
26 31661763 Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review. 2019 Oct 28 3
27 29529257 Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease. 2018 Jun 7 3
28 29920211 The combination of single nucleotide polymorphisms rs6720173 (ABCG5), rs3808607 (CYP7A1), and rs760241 (DHCR7) is associated with differing serum cholesterol responses to dairy consumption. 2018 Oct 1
29 30354296 Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression. 2018 Oct 4
30 30500001 Stilbenoids and cannabinoids from the leaves of Cannabis sativa f. sativa with potential reverse cholesterol transport activity. 2018 Dec 13 1
31 27629819 Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages. 2017 Feb 1
32 28302129 Cholesterol-lowing effect of taurine in HepG2 cell. 2017 Mar 16 2
33 28357032 Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease. 2017 Mar 18 2
34 29171472 [CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism]. 2017 1
35 26663205 A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism. 2016 Jul 1
36 26848702 Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters. 2016 May 1
37 26876917 Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters. 2016 Apr 15 1
38 26932749 Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population. 2016 Jun 1
39 26936139 High-Molecular-Weight β-Glucan Decreases Serum Cholesterol Differentially Based on the CYP7A1 rs3808607 Polymorphism in Mildly Hypercholesterolemic Adults. 2016 Apr 1
40 27052530 Common Variants in Cholesterol Synthesis- and Transport-Related Genes Associate with Circulating Cholesterol Responses to Intakes of Conventional Dairy Products in Healthy Individuals. 2016 May 2
41 27218859 Determination of 7α-OH cholesterol by LC-MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs. 2016 Jul 1 1
42 27406814 Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes. 2016 Oct 1
43 27570155 Quantitative Metabolomic Profiling of Plasma, Urine, and Liver Extracts by 1H NMR Spectroscopy Characterizes Different Stages of Atherosclerosis in Hamsters. 2016 Oct 7 1
44 27713083 The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation. 2016 Dec 1
45 25944972 CYP7A1 gene polymorphism located in the 5' upstream region modifies the risk of coronary artery disease. 2015 2
46 26281596 [Regulatory effect of coptisine on key genes involved in cholesterol metabolism]. 2015 Apr 1
47 26333513 CYP7A1-rs3808607 and APOE isoform associate with LDL cholesterol lowering after plant sterol consumption in a randomized clinical trial. 2015 Oct 3
48 26345803 Correlation between the decrease of cholesterol efflux from macrophages in patients with type II diabetes mellitus and down-regulated CYP7A1 expression. 2015 Jul 31 2
49 26365577 Intake of grape procyanidins during gestation and lactation impairs reverse cholesterol transport and increases atherogenic risk indexes in adult offspring. 2015 Dec 1
50 24361308 Effects of a farnesoid X receptor antagonist on hepatic lipid metabolism in primates. 2014 Jan 15 1