Triglycerides

patatin like phospholipase domain containing 2 ; Homo sapiens







105 Article(s)
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1 35065923 Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation. 2022 Mar 3
2 35372814 The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy. 2022 Apr 15 2
3 33219129 ABHD5 suppresses cancer cell anabolism through lipolysis-dependent activation of the AMPK/mTORC1 pathway. 2021 Jan-Jun 1
4 33231284 Outside-in signaling by femoral cuff injury induces a distinct vascular lesion in adipose triglyceride lipase knockout mice. 2021 Jan 1
5 33246168 Farnesol induces mitochondrial/peroxisomal biogenesis and thermogenesis by enhancing the AMPK signaling pathway in vivo and in vitro. 2021 Jan 1
6 33484445 Low Molecular Pectin Inhibited the Lipid Accumulation by Upregulation of METTL7B. 2021 May 2
7 33621408 Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway. 2021 Apr 1
8 34352257 Morphine increases myocardial triacylglycerol through regulating adipose triglyceride lipase S406 phosphorylation. 2021 Oct 15 6
9 34508728 A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity. 2021 1
10 34543623 Optimized expression and purification of adipose triglyceride lipase improved hydrolytic and transacylation activities in vitro. 2021 Oct 2
11 32234723 Adipose Triglyceride Lipase is a Key Lipase for the Mobilization of Lipid Droplets in Human Beta Cells and Critical for the Maintenance of Syntaxin1a Level in Beta Cells. 2020 Mar 31 3
12 32312867 Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells. 2020 Jun 8
13 32417386 Regulation of lipid droplet homeostasis by hypoxia inducible lipid droplet associated HILPDA. 2020 Sep 1
14 32454271 Effect of salt promote the muscle triglyceride hydrolysis during dry-salting by inducing the phosphorylation of adipose tissue triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) and lipid droplets splitting. 2020 Oct 15 2
15 32542055 The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly. 2020 Jun 1
16 32564019 Neutral Lipid Storage Disease Associated with the PNPLA2 Gene: Case Report and Literature Review. 2020 1
17 32705602 CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis. 2020 1
18 30367149 Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53. 2019 Mar 1
19 30367950 Of mice and men: The physiological role of adipose triglyceride lipase (ATGL). 2019 Jun 2
20 30738494 Clinical findings and autophagic pathology in neutral lipid storage disease with myopathy. 2019 Jul/Aug 2
21 30918066 PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells. 2019 Jun 2
22 31035700 An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis. 2019 Apr 29 4
23 31049523 Polysaccharides derived from natural sources regulate triglyceride and cholesterol metabolism: a review of the mechanisms. 2019 May 22 1
24 31186072 Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder. 2019 Jun 11 3
25 31497752 Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes. 2019 May 6
26 28925902 Adipose Triglyceride Lipase Regulation: An Overview. 2018 2
27 29146190 Newly developed selective immunoinactivation assay revealed reduction in adipose triglyceride lipase activity in peripheral leucocytes from patients with idiopathic triglyceride deposit cardiomyovasculopathy. 2018 Jan 1 3
28 29457907 Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells. 2018 Apr 6 4
29 29527681 Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise. 2018 Jun 2
30 30352762 Neutral lipid storage disease with myopathy and dropped head syndrome. Report of a new variant susceptible of treatment with late diagnosis. 2018 Dec 1
31 28179319 Adipose Triglyceride Lipase (ATGL) Expression Is Associated with Adiposity and Tumor Stromal Proliferation in Patients with Pancreatic Ductal Adenocarcinoma. 2017 Feb 1
32 28456765 The skeletal and heart muscle triacylglycerol lipolysis revisited. 2017 Feb 2
33 28548386 Design and synthesis of Atglistatin derivatives as adipose triglyceride lipase inhibitors. 2017 Dec 1
34 28928121 Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes. 2017 Dec 1
35 26471343 Contribution of lipase deficiency to mitochondrial dysfunction and insulin resistance in hMADS adipocytes. 2016 Mar 1
36 26529279 Lipolytic and thermogenic depletion of adipose tissue in cancer cachexia. 2016 Jun 1
37 26745266 Reassessing the Potential Activities of Plant CGI-58 Protein. 2016 2
38 27056902 Adipose triglyceride lipase decrement affects skeletal muscle homeostasis during aging through FAs-PPARα-PGC-1α antioxidant response. 2016 Apr 26 1
39 27155760 New Atglistatin closely related analogues: Synthesis and structure-activity relationship towards adipose triglyceride lipase inhibition. 2016 Aug 8 2
40 27213586 Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. 2016 Jun 7 2
41 27396333 Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation. 2016 Jul 26 2
42 27408777 G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle. 2016 Jul 1
43 27565982 Detection of four polymorphisms in 5' upstream region of PNPLA2 gene and their associations with economic traits in pigs. 2016 Nov 2
44 25287355 A myopathy with unusual features caused by PNPLA2 gene mutations. 2015 Apr 2
45 25890298 PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL. 2015 Feb 21 1
46 25904333 ELMOD2 is anchored to lipid droplets by palmitoylation and regulates adipocyte triglyceride lipase recruitment. 2015 Jun 15 2
47 25956450 Novel missense mutations in PNPLA2 causing late onset and clinical heterogeneity of neutral lipid storage disease with myopathy in three siblings. 2015 Jun-Jul 4
48 26075089 The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells. 2015 1
49 26318046 Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells. 2015 Sep 29 2
50 26350461 Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring. 2015 Oct 30 2