Acetylcysteine

transforming growth factor beta 1 ; Homo sapiens







42 Article(s)
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1 34993544 Generation of endoplasmic reticulum stress-dependent reactive oxygen species mediates TGF-β1-induced podocyte migration. 2022 Mar 3 3
2 31906396 Melatonin Prevents Transforming Growth Factor-β1-Stimulated Transdifferentiation of Renal Interstitial Fibroblasts to Myofibroblasts by Suppressing Reactive Oxygen Species-Dependent Mechanisms. 2020 Jan 1 1
3 32104284 Effects of tetrandrine combined with acetylcysteine on exercise tolerance, pulmonary function and serum TNF-β1 and MMP-7 in silicosis patients. 2020 Mar 1
4 32736702 Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells. 2020 Aug 27 1
5 31127990 Effect of TGF-β1 on Apoptosis of Colon Cancer Cells Via the ERK Signaling Pathway. 2019 Mar-Apr 2
6 31717992 Melatonin Inhibits Transforming Growth Factor-β1-Induced Epithelial-Mesenchymal Transition in AML12 Hepatocytes. 2019 Nov 11 1
7 31934265 Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells. 2019 1
8 28815354 NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway. 2018 Feb 1
9 29408318 Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-β) pathways in placental JEG-3 trophoblast cells via reactive oxygen species. 2018 Mar 1 1
10 30191979 Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell. 2018 Jan 1
11 30307163 Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells 2018 Oct 1 2
12 28405169 Oxidant-induced autophagy and ferritin degradation contribute to epithelial-mesenchymal transition through lysosomal iron. 2017 2
13 29039574 TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK. 2017 Dec 1
14 29049376 Antioxidants and NOX1/NOX4 inhibition blocks TGFβ1-induced CCN2 and α-SMA expression in dermal and gingival fibroblasts. 2017 3
15 27061477 The effect of N-acetylcysteine and calcium hydroxide on TNF-α and TGF-β1 in lipopolysaccharide-activated macrophages. 2016 Aug 1
16 27576730 Metformin attenuates lung fibrosis development via NOX4 suppression. 2016 Aug 30 2
17 25406100 Titanium nanoparticle inhalation induces renal fibrosis in mice via an oxidative stress upregulated transforming growth factor-β pathway. 2015 Mar 16 1
18 24691097 Inhibitory role of the KEAP1-NRF2 pathway in TGFβ1-stimulated renal epithelial transition to fibroblastic cells: a modulatory effect on SMAD signaling. 2014 2
19 23281030 Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells. 2013 Mar 1
20 23687429 The protective effect of antioxidants on orbital fibroblasts from patients with Graves' ophthalmopathy in response to oxidative stress. 2013 1
21 24048773 N-Acetylcysteine effects on transforming growth factor-β and tumor necrosis factor-α serum levels as pro-fibrotic and inflammatory biomarkers in patients following ST-segment elevation myocardial infarction. 2013 Sep 2
22 21131394 TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells. 2011 Feb 3
23 21173077 Retinoic acid stimulation of VEGF secretion from human endometrial stromal cells is mediated by production of reactive oxygen species. 2011 Feb 15 1
24 22129737 Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts. 2011 1
25 19751964 Transforming growth factorbeta(1) transactivates EGFR via an H(2)O(2)-dependent mechanism in squamous carcinoma cell line. 2010 Apr 1 1
26 20177149 Co-treatment with hepatocyte growth factor and TGF-beta1 enhances migration of HaCaT cells through NADPH oxidase-dependent ROS generation. 2010 Apr 30 1
27 20204677 ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion. 2010 Jul 1
28 20583212 Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth. 2010 Sep 1
29 19393328 N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts. 2009 Dec 2
30 19398917 N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress. 2009 Aug 8
31 20560295 N-acetylcysteine inhibits TNF-alpha, sTNFR, and TGF-beta1 release by alveolar macrophages in idiopathic pulmonary fibrosis in vitro. 2009 Jul 3
32 15979845 Cooperation of H2O2-mediated ERK activation with Smad pathway in TGF-beta1 induction of p21WAF1/Cip1. 2006 Feb 2
33 16757516 Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. 2006 Jul 1 1
34 16098950 N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug. 2005 Oct 1 6
35 15178409 Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts. 2004 Jun 25 1
36 15203191 Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species. 2004 Jul 15 3
37 12631112 Advanced glycation end products inhibit de novo protein synthesis and induce TGF-beta overexpression in proximal tubular cells. 2003 Feb 1
38 13679067 Reactive oxygen species mediate TGF-beta1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells. 2003 Oct 3 1
39 11062741 Antiapoptotic and antigenotoxic effects of N-acetylcysteine in human cells of endothelial origin. 2000 Sep-Oct 1
40 10365774 Reduction of endothelial cell related TGFbeta activity by thiols. 1999 2
41 8670763 Transforming growth factor beta-1 and beta-2 in human tear fluid. 1996 Jun 2
42 8853906 Transforming growth factor beta 1-induced apoptosis in human ovarian carcinoma cells: protection by the antioxidant N-acetylcysteine and bcl-2. 1996 Aug 2