Dexmedetomidine

high mobility group box 1 ; Rattus norvegicus







14 Article(s)
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1 35486975 Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway. 2022 Jun 3
2 33748118 Abnormal Rat Cortical Development Induced by Ventricular Injection of rHMGB1 Mimics the Pathophysiology of Human Cortical Dysplasia. 2021 2
3 34162568 Dexmedetomidine Attenuates Myocardial Injury Induced by Renal Ischemia/Reperfusion by Inhibiting the HMGB1-TLR4-MyD88-NF-κB Signaling Pathway. 2021 May 1
4 34196265 Dexmedetomidine inhibits inflammatory response and oxidative stress through regulating miR-205-5p by targeting HMGB1 in cerebral ischemic/reperfusion. 2021 Aug 7
5 31912804 Dexmedetomidine Post-Conditioning Alleviates Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting High Mobility Group Protein B1 Group (HMGB1)/Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling Pathway. 2020 Jan 8 4
6 32607919 Dexmedetomidine Alleviates CCI-Induced Neuropathic Pain via Inhibiting HMGB1-Mediated Astrocyte Activation and the TLR4/NF-κB Signaling Pathway in Rats. 2020 Oct 5
7 32707303 Dexmedetomidine ameliorates renal ischemia reperfusion-mediated activation of the NLRP3 inflammasome in alveolar macrophages. 2020 Oct 20 2
8 31344138 Dexmedetomidine-induced cardioprotection is mediated by inhibition of high mobility group box-1 and the cholinergic anti-inflammatory pathway in myocardial ischemia-reperfusion injury. 2019 4
9 29241031 The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways. 2018 Feb 1
10 27998004 Dexmedetomidine preconditioning for myocardial protection in ischaemia-reperfusion injury in rats by downregulation of the high mobility group box 1-toll-like receptor 4-nuclear factor κB signalling pathway. 2017 Mar 4
11 28222157 Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway. 2017 5
12 29312480 Dexmedetomidine mitigates CLP-stimulated acute lung injury via restraining the RAGE pathway. 2017 1
13 26418907 Stimulation of Central α2 Receptors Attenuates Experimental Necrotizing Pancreatitis. 2016 Feb 1
14 26408618 [Effect of dexmedetomidine on high-mobility group box 1 protein in rats with sepsis]. 2015 Sep 5