| 1 |
31634532 | Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis. | 2020 Jan |
1 |
| 2 |
31842697 | Discovery of selective farnesoid X receptor agonists for the treatment of hyperlipidemia from traditional Chinese medicine based on virtual screening and in vitro validation. | 2020 Sep |
1 |
| 3 |
29466845 | Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease. | 2019 Jul |
1 |
| 4 |
30896855 | Activation of FXR by obeticholic acid induces hepatic gene expression of SR-BI through a novel mechanism of transcriptional synergy with the nuclear receptor LXR. | 2019 May |
1 |
| 5 |
29134430 | Modern drug design: the implication of using artificial neuronal networks and multiple molecular dynamic simulations. | 2018 Jan |
1 |
| 6 |
29456791 | Nonacidic Chemotype Possessing N-Acylated Piperidine Moiety as Potent Farnesoid X Receptor (FXR) Antagonists. | 2018 Feb 8 |
1 |
| 7 |
30275017 | Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding. | 2018 Nov 23 |
1 |
| 8 |
27940481 | Regulation of lipid metabolism by obeticholic acid in hyperlipidemic hamsters. | 2017 Feb |
2 |
| 9 |
28338522 | Developments in intestinal cholesterol transport and triglyceride absorption. | 2017 Jun |
3 |
| 10 |
26607331 | Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity. | 2016 Jan |
1 |
| 11 |
26812075 | Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid. | 2016 May |
1 |
| 12 |
24575869 | Probiotics and the BSH-related cholesterol lowering mechanism: a Jekyll and Hyde scenario. | 2015 |
1 |
| 13 |
25659870 | Nuclear receptors and cholesterol metabolism in the intestine. | 2015 Feb |
4 |
| 14 |
25982493 | Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal Farnesoid X Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism. | 2015 Jul |
1 |
| 15 |
26598835 | Functions of Cholesterol Metabolites. | 2015 |
2 |
| 16 |
24685112 | Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR). | 2014 Apr 15 |
1 |
| 17 |
24775917 | Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor. | 2014 Jun 1 |
1 |
| 18 |
25388534 | Recent advances in non-steroidal FXR antagonists development for therapeutic applications. | 2014 |
1 |
| 19 |
23206728 | Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis. | 2013 Jan |
2 |
| 20 |
23374727 | Nomilin as an anti-obesity and anti-hyperglycemic agent. | 2013 |
1 |
| 21 |
23619224 | [Nutrigenomics--bioactive dietary components]. | 2013 Apr 5 |
2 |
| 22 |
23620138 | Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice. | 2013 Aug |
1 |
| 23 |
24041925 | Upregulation of thrombomodulin expression by activation of farnesoid X receptor in vascular endothelial cells. | 2013 Oct 15 |
1 |
| 24 |
24222091 | Bile acid-mediated control of liver triglycerides. | 2013 Nov |
1 |
| 25 |
21707484 | The gut-to-breast connection - interdependence of sterols and sphingolipids in multidrug resistance and breast cancer therapy. | 2011 Nov |
1 |
| 26 |
19913492 | Identification of farnesoid X receptor modulators by a fluorescence polarization-based interaction assay. | 2010 Mar 15 |
1 |
| 27 |
20569093 | Farnesoid X receptor modulators: a patent review. | 2010 Aug |
1 |
| 28 |
20956002 | Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte. | 2010 Dec |
1 |
| 29 |
18391212 | Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation. | 2008 Apr 8 |
1 |
| 30 |
18603830 | The novel compounds that activate farnesoid X receptor: the diversity of their effects on gene expression. | 2008 Jul |
1 |
| 31 |
18779653 | Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes. | 2008 Aug 31 |
2 |
| 32 |
17307356 | 3D-QSAR studies with the aid of molecular docking for a series of non-steroidal FXR agonists. | 2007 Apr 15 |
1 |
| 33 |
17071613 | Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration. | 2006 Dec 22 |
1 |
| 34 |
15329387 | Ligand-dependent coactivation of the human bile acid receptor FXR by the peroxisome proliferator-activated receptor gamma coactivator-1alpha. | 2005 Jan |
1 |
| 35 |
15725701 | Nuclear receptors as targets for drug development: regulation of cholesterol and bile acid metabolism by nuclear receptors. | 2005 Feb |
1 |
| 36 |
15832810 | Induction of phase I, II and III drug metabolism/transport by xenobiotics. | 2005 Mar |
1 |
| 37 |
15911693 | The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes. | 2005 Aug |
1 |
| 38 |
16178789 | Role of FXR in regulating bile acid homeostasis and relevance for human diseases. | 2005 Sep |
1 |
| 39 |
13130122 | Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation. | 2004 Jan |
1 |
| 40 |
15145977 | Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor. | 2004 Aug |
1 |
| 41 |
15187081 | Identification of DRIP205 as a coactivator for the Farnesoid X receptor. | 2004 Aug 27 |
1 |
| 42 |
12559450 | The coming of age of our understanding of the enterohepatic circulation of bile salts. | 2003 Feb |
3 |
| 43 |
12704471 | The role of the enterohepatic circulation of bile salts and nuclear hormone receptors in the regulation of cholesterol homeostasis: Bile salts as ligands for nuclear hormone receptors. | 2003 Apr |
3 |
| 44 |
12718892 | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. | 2003 Apr |
1 |
| 45 |
14733360 | Ligand-binding domain of farnesoid X receptor (FXR) had the highest sensitivity and activity among FXR variants in a fluorescence-based assay. | 2003 Nov |
1 |
| 46 |
14992012 | [On the bile acid receptor FXR]. | 2003 Oct |
1 |