NADP

aldo-keto reductase family 1 member B ; Homo sapiens







97 Article(s)
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1 35158093 Phosphoproteome of signaling by ErbB2 in ovarian cancer cells. 2022 Apr 1 1
2 35388067 Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study. 2022 Apr 6 3
3 35454074 In Search of Differential Inhibitors of Aldose Reductase. 2022 Mar 22 2
4 32208122 Exploration of Diosmin to Control Diabetes and Its Complications-an In Vitro and In Silico Approach. 2021 1
5 32734850 Inhibitory effects of curcumin on aldose reductase and cyclooxygenase-2 enzymes. 2021 Oct 2
6 33494154 Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems. 2021 Jan 21 2
7 25376835 Reduction of lipid peroxidation products and advanced glycation end-product precursors by cyanobacterial aldo-keto reductase AKR3G1—a founding member of the AKR3G subfamily. 2015 Jan 1
8 25532697 Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10. 2015 Jun 5 1
9 24817585 Identification and functional characterization of sorbitol-6-phosphate dehydrogenase protein from rice and structural elucidation by in silico approach. 2014 Jul 1
10 24974084 Induced fit docking, pharmacophore modeling, and molecular dynamic simulations on thiazolidinedione derivatives to explore key interactions with Tyr48 in polyol pathway. 2014 Jul 3
11 23295227 X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. 2013 Feb 25 1
12 22249747 Pharmacophore modeling, molecular docking, and molecular dynamics simulation approaches for identifying new lead compounds for inhibiting aldose reductase 2. 2012 Jul 2
13 22505406 Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH. 2012 Apr 1 2
14 21306562 Catalytic mechanism of the primary human prostaglandin F2α synthase, aldo-keto reductase 1B1--prostaglandin D2 synthase activity in the absence of NADP(H). 2011 Apr 5
15 21319207 Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors. 2011 Jun 2
16 21859105 Electrostatic fields near the active site of human aldose reductase: 2. New inhibitors and complications caused by hydrogen bonds. 2011 Oct 4 1
17 20218967 3D-QSAR Studies on a Series of 5-Arylidine-2, 4-Thiazolidinediones as Aldose Reductase Inhibitors: A Self-Organizing Molecular Field Analysis Approach. 2010 Mar 11 2
18 20402658 3D-QSAR studies on a series of 5-arylidine-2, 4-thiazolidinediones as aldose reductase inhibitors: a self-organizing molecular field analysis approach. 2010 Jan 2
19 19010934 Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7. 2009 Feb 1
20 19013440 Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes. 2009 Mar 16 3
21 19301313 Structure-based optimization of aldose reductase inhibitors originating from virtual screening. 2009 May 2
22 19602579 Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy. 2009 Sep 1
23 18451330 Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis. 2008 Jun 2
24 18537622 From a dull enzyme to something else: facts and perspectives regarding aldose reductase. 2008 1
25 16622654 Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase-inhibitor complex. 2006 Sep 1
26 17139089 Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat. 2006 Dec 1
27 15769597 The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism. 2005 May 15 3
28 15146478 Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A. 2004 Jun 1 1
29 12604217 Hydrogen bonding interactions between aldose reductase complexed with NADP(H) and inhibitor tolrestat studied by molecular dynamics simulations and binding assay. 2003 Feb 1 8
30 12604221 Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase. 2003 Feb 1 1
31 12732097 Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism. 2003 Aug 1 2
32 12855766 Electrostatic complementarity in an aldose reductase complex from ultra-high-resolution crystallography and first-principles calculations. 2003 Jul 22 1
33 12871133 Recent studies of aldose reductase enzyme inhibition for diabetic complications. 2003 Aug 2
34 12871134 Aldose reductase inhibitors from the nature. 2003 Aug 2
35 14615967 Aldose reductase catalyzes reduction of the lipid peroxidation product 4-oxonon-2-enal. 2003 Nov 1
36 14641065 Aldose reductase and the importance of experimental design. 2003 Dec 3
37 11958479 Aldose reductase: an aldehyde scavenging enzyme in the intraneuronal metabolism of norepinephrine in human sympathetic ganglia. 2002 Mar 18 1
38 11444967 Stereospecific interaction of a novel spirosuccinimide type aldose reductase inhibitor, AS-3201, with aldose reductase. 2001 Jul 27 2
39 12164386 Aldose reductase inhibitors. 2001 Dec 1
40 10706394 Inhibitory effects of fidarestat on aldose reductase and aldehyde reductase activity evaluated by a new method using HPLC with post-column spectrophotometric detection. 2000 Feb 1
41 10933817 The sorbinil trap: a predicted dead-end complex confirms the mechanism of aldose reductase inhibition. 2000 Aug 15 1
42 10997684 Aldose reductase and the role of the polyol pathway in diabetic nephropathy. 2000 Sep 4
43 9884310 Aldose reductase catalyzes the oxidation of naphthalene-1, 2-dihydrodiol for the formation of ortho-naphthoquinone. 1999 Jan 1
44 10493777 Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites. 1999 Sep 3 1
45 9546197 Catalytic mechanism of aldose reductase studied by the combined potentials of quantum mechanics and molecular mechanics. 1998 Mar 9 1
46 9871575 Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor tolrestat. 1998 Mar 17 1
47 9000650 Restoration of nitric oxide production by aldose reductase inhibitor in human endothelial cells cultured in high-glucose medium. 1997 2
48 9195881 A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. 1997 May 15 4
49 9307017 NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme. 1997 Sep 15 1
50 9398310 Modification of aldose reductase by S-nitrosoglutathione. 1997 Dec 16 1