| 1 |
29458045 | Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction. | 2018 Apr |
2 |
| 2 |
28600556 | Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity. | 2017 Jun 9 |
2 |
| 3 |
28740855 | Aldose Reductase Inhibitor Protects against Hyperglycemic Stress by Activating Nrf2-Dependent Antioxidant Proteins. | 2017 |
1 |
| 4 |
26163626 | Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study. | 2015 |
1 |
| 5 |
24607578 | Development of novel pyrazolone derivatives as inhibitors of aldose reductase: an eco-friendly one-pot synthesis, experimental screening and in silico analysis. | 2014 Apr |
1 |
| 6 |
23295227 | X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. | 2013 Feb 25 |
2 |
| 7 |
23732517 | Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors. | 2013 Oct |
1 |
| 8 |
21354119 | Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. | 2011 May 30 |
1 |
| 9 |
21576240 | Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells. | 2011 Jul 8 |
2 |
| 10 |
19594152 | Charge density and electrostatic interactions of fidarestat, an inhibitor of human aldose reductase. | 2009 Aug 12 |
1 |
| 11 |
18284183 | Unusual binding mode of the 2S4R stereoisomer of the potent aldose reductase cyclic imide inhibitor fidarestat (2S4S) in the 15 K crystal structure of the ternary complex refined at 0.78 A resolution: implications for the inhibition mechanism. | 2008 Mar 13 |
1 |
| 12 |
17063327 | Effect of the aldose reductase inhibitor fidarestat on experimental diabetic neuropathy in the rat. | 2006 Dec |
2 |
| 13 |
16134934 | Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex. | 2005 Sep 8 |
2 |
| 14 |
15317464 | High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor. | 2004 Aug 26 |
1 |
| 15 |
15561956 | Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice. | 2004 Dec |
1 |
| 16 |
12039395 | Fidarestat (SNK-860), a potent aldose reductase inhibitor, normalizes the elevated sorbitol accumulation in erythrocytes of diabetic patients. | 2002 Mar-Apr |
1 |
| 17 |
11359994 | Pharmacological properties of fidarestat, a potent aldose reductase inhibitor, clarified by using sorbitol in human and rat erythrocytes. | 2001 May |
1 |
| 18 |
11574441 | Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study. | 2001 Oct |
3 |
| 19 |
10706394 | Inhibitory effects of fidarestat on aldose reductase and aldehyde reductase activity evaluated by a new method using HPLC with post-column spectrophotometric detection. | 2000 Feb |
1 |