Flavonoids

UDP glucuronosyltransferase family 1 member A1 ; Homo sapiens







19 Article(s)
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1 35241486 Inhibition of Human UDP-Glucuronosyltransferases1A1-Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice. 2022 May 4
2 33628187 Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARĪ± and PPARĪ³. 2020 4
3 30594625 Inhibition of UGT1A1 by natural and synthetic flavonoids. 2019 Apr 1 16
4 31872743 [Prediction of potential drug interactions of apigenin based on molecular docking and in vitro inhibition experiments]. 2019 Sep 1
5 29584932 Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids. 2018 Jul 1 1
6 26833852 Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. 2016 Sep 1
7 26066637 Decreased Expression of Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Leads to Reduced Glucuronidation of Flavonoids in UGT1A1-Overexpressing HeLa Cells: The Role of Futile Recycling. 2015 Jul 8 1
8 24375494 Analysis of flavonoids regulating the expression of UGT1A1 via xenobiotic receptors in intestinal epithelial cells. 2014 May-Jun 2
9 23786524 Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids. 2013 Aug 5 5
10 21933112 Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis. 2011 Nov 1
11 21985641 Evaluation of 3,3',4'-trihydroxyflavone and 3,6,4'-trihydroxyflavone (4'-O-glucuronidation) as the in vitro functional markers for hepatic UGT1A1. 2011 Dec 5 5
12 19034627 Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. 2009 Apr 1
13 17256720 The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice. 2007 Feb 2
14 15104253 The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics. 2004 Mar 1 6
15 11950788 Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. 2002 May 4
16 12018987 Regioselectivity of phase II metabolism of luteolin and quercetin by UDP-glucuronosyl transferases. 2002 May 1
17 11442279 Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation. 2001 Mar 2
18 10950852 Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in the human hepatoma cell line hep G2. 2000 Sep 1
19 8806713 The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. 1996 Aug 1 1