| 1 |
35074429 | The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor. | 2022 Mar |
1 |
| 2 |
34358111 | Interaction between DNA, Albumin and Apo-Transferrin and Iridium(III) Complexes with Phosphines Derived from Fluoroquinolones as a Potent Anticancer Drug. | 2021 Jul 16 |
1 |
| 3 |
31748790 | Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization. | 2020 Jan 1 |
1 |
| 4 |
31899992 | Arg1201Gln mutation of insulin receptor impairs tyrosine kinase activity and causes insulin resistance: a case report. | 2020 Jun |
1 |
| 5 |
32409919 | Characterization of Huh7 cells after the induction of insulin resistance and post-treatment with metformin. | 2020 Aug |
1 |
| 6 |
32888269 | Potential Inhibitors of Protein Tyrosine Phosphatase (PTP1B) Enzyme: Promising Target for Type-II Diabetes Mellitus. | 2020 |
1 |
| 7 |
32896381 | N-myristoylation regulates insulin-induced phosphorylation and ubiquitination of Caveolin-2 for insulin signaling. | 2020 Nov 19 |
2 |
| 8 |
32964344 | Insulin Resistance the Hinge Between Hypertension and Type 2 Diabetes. | 2020 Dec |
1 |
| 9 |
31333090 | Protein Tyrosine Phosphatase 1B Inhibitors: A Novel Therapeutic Strategy for the Management of type 2 Diabetes Mellitus. | 2019 |
1 |
| 10 |
31827016 | Structure and function of the insulin receptor-a personal perspective. | 2019 |
4 |
| 11 |
31872693 | [Overview on hypoglycemic active constituents of traditional Chinese medicine based on insulin receptor signaling pathway]. | 2019 Oct |
1 |
| 12 |
32422022 | Hyperactivated Insulin Signaling Cascade in Human Glioblastoma Cells. | 2019 |
2 |
| 13 |
26584640 | mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. | 2016 Jan |
1 |
| 14 |
27155325 | Novel method demonstrates differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation. | 2016 Aug |
3 |
| 15 |
27514532 | IRS proteins and diabetic complications. | 2016 Nov |
1 |
| 16 |
25342129 | Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease. | 2015 Feb |
1 |
| 17 |
25604425 | Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin. | 2015 Jan 21 |
1 |
| 18 |
25667086 | Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. | 2015 May |
10 |
| 19 |
25687571 | The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network. | 2015 Apr |
1 |
| 20 |
25693802 | Quantitative phosphoproteomics analysis reveals a key role of insulin growth factor 1 receptor (IGF1R) tyrosine kinase in human sperm capacitation. | 2015 Apr |
1 |
| 21 |
25730798 | An extract of Perilla stem inhibits Src homology phosphatase-1 (SHP)-1 and influences insulin signaling. | 2015 Mar |
2 |
| 22 |
25864925 | Tumor vessel up-regulation of INSR revealed by single-cell expression analysis of the tyrosine kinome and phosphatome in human cancers. | 2015 Jun |
1 |
| 23 |
26063811 | The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites. | 2015 Sep |
3 |
| 24 |
26345813 | Insulin receptor binding motif tagged with IgG4 Fc (Yiminsu) works as an insulin sensitizer to activate Akt signaling in hepatocytes. | 2015 Aug 3 |
2 |
| 25 |
26569375 | Controlling in Vitro Insulin Amyloidosis with Stable Peptide Conjugates: A Combined Experimental and Computational Study. | 2015 Dec 17 |
1 |
| 26 |
24264858 | Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance. | 2014 Mar |
1 |
| 27 |
24341419 | Trying to understand gestational diabetes. | 2014 Mar |
1 |
| 28 |
24939305 | Relationship between tyrosine phosphorylation and protein expression of insulin receptor and insulin resistance in gestational diabetes mellitus. | 2014 Jun |
3 |
| 29 |
25259572 | Insulin resistance induced by hyperinsulinemia coincides with a persistent alteration at the insulin receptor tyrosine kinase domain. | 2014 |
1 |
| 30 |
22972224 | Leprechaunism (Donohue syndrome): a case bearing novel compound heterozygous mutations in the insulin receptor gene. | 2013 |
3 |
| 31 |
23225242 | Decreased phosphorylation of Y¹⁴caveolin-1 in endometrial tissue of polycystic ovary syndrome patients may be related with an insulin resistant state in this tissue. | 2013 Apr |
2 |
| 32 |
23457259 | The insulin receptor: both a prototypical and atypical receptor tyrosine kinase. | 2013 Mar 1 |
5 |
| 33 |
23700321 | Testosterone modulates the expression of molecules linked to insulin action and glucose uptake in endometrial cells. | 2013 Sep |
1 |
| 34 |
22403294 | A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control. | 2012 May |
2 |
| 35 |
22609131 | From excess adiposity to insulin resistance: the role of free fatty acids. | 2012 Sep-Oct |
2 |
| 36 |
22768670 | A novel mutation of the insulin receptor gene in a preterm infant with Donohue syndrome and heart failure. | 2012 |
1 |
| 37 |
22992069 | Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family. | 2012 Dec 1 |
1 |
| 38 |
23108067 | Effects of increased fetuin-A in human trophoblast cells and associated pregnancy outcomes. | 2012 Dec |
1 |
| 39 |
21168390 | Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases. | 2011 Jan 21 |
2 |
| 40 |
21205932 | Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains. | 2011 Mar |
1 |
| 41 |
21680660 | Research resource: New and diverse substrates for the insulin receptor isoform A revealed by quantitative proteomics after stimulation with IGF-II or insulin. | 2011 Aug |
2 |
| 42 |
21841811 | Activating transcription factor 6 protects insulin receptor from ER stress-stimulated desensitization via p42/44 ERK pathway. | 2011 Sep |
1 |
| 43 |
22110065 | Role of β-adrenergic receptor regulation of TNF-α and insulin signaling in retinal Muller cells. | 2011 Dec 16 |
2 |
| 44 |
19895792 | Prolonged tyrosine kinase activation of insulin receptor by pY27-caveolin-2. | 2010 Jan 1 |
2 |
| 45 |
20049867 | Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways. | 2010 Mar |
1 |
| 46 |
18983503 | Insulin inhibits tissue factor expression in monocytes. | 2009 Jan |
1 |
| 47 |
19079291 | Over-expression of NYGGF4 inhibits glucose transport in 3T3-L1 adipocytes via attenuated phosphorylation of IRS-1 and Akt. | 2009 Jan |
1 |
| 48 |
19277985 | Insulin receptor kinase-independent signaling via tyrosine phosphorylation of phosphatase PHLPP1. | 2009 May 1 |
1 |
| 49 |
19381127 | Insulin resistance and steatosis in chronic hepatitis C. | 2009 |
1 |
| 50 |
19497338 | Insulin induced phosphorylation of prohibitin at tyrosine 114 recruits Shp1. | 2009 Aug |
2 |