geldanamycin

heat shock protein 90 beta family member 1 ; Homo sapiens







15 Article(s)
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1 31523389 Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis. 2019 Sep 3 1
2 20942857 The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery? 2011 Jan 1
3 19875450 Cell-surface processing of the metalloprotease pro-ADAMTS9 is influenced by the chaperone GRP94/gp96. 2010 Jan 1 1
4 20977755 The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1. 2010 Oct 26 1
5 19361515 Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design. 2009 May 22 2
6 12713659 Inhibition of complex glycosylation increases the formation of PrPsc. 2003 May 3
7 12446770 Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. 2002 Dec 3
8 11071886 Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90. 2001 Feb 2 1
9 10806200 Intracellular retention and degradation of the epidermal growth factor receptor, two distinct processes mediated by benzoquinone ansamycins. 2000 Jul 21 2
10 10816561 Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. I. Evidence for allosteric regulation of ligand binding. 2000 Jul 28 1
11 9428803 Geldanamycin, an hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway. 1998 Feb 2
12 9622079 Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations. 1998 Jun 1 1
13 9843494 Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. 1998 Dec 1 1
14 8617772 p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2. 1996 Mar 1 1
15 8798456 Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin. 1996 Sep 13 2