Guanine Nucleotides

alsin Rho guanine nucleotide exchange factor ; Mus musculus







3 Article(s)
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1 20339559 Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking. 2010 Mar 22 2
2 16321985 Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking. 2006 Jan 15 2
3 15579468 A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. 2005 Feb 11 1