Wortmannin

leptin ; Homo sapiens







18 Article(s)
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1 25644212 Effects of recombinant human leptin administration on hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco: in vivo and in vitro studies. 2015 Feb 1 3
2 22771801 Effects of C-reactive protein on adipokines genes expression in 3T3-L1 adipocytes. 2012 Aug 3 1
3 23300886 Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways. 2012 1
4 21334313 Leptin amplifies the action of thyrotropin-releasing hormone in the solitary nucleus: an in vitro calcium imaging study. 2011 Apr 18 1
5 21371463 Leptin reduces gentamicin-induced apoptosis in rat renal tubular cells via the PI3K-Akt signaling pathway. 2011 May 11 2
6 22122897 Butyrate regulates leptin expression through different signaling pathways in adipocytes. 2011 Dec 1
7 19643094 Leptin "gates" thermogenic action of thyrotropin-releasing hormone in the hindbrain. 2009 Oct 27 1
8 18340408 Leptin protection of salivary gland acinar cells against ethanol cytotoxicity involves Src kinase-mediated parallel activation of prostaglandin and constitutive nitric oxide synthase pathways. 2008 Apr 1
9 18501560 Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts. 2008 Aug 1
10 18767036 Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways. 2008 Dec 1 2
11 17617622 Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. 2007 Jul 15 1
12 16497805 Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase- dependent mechanism. 2006 May 1
13 16752079 Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1. 2006 Jul 1
14 17072262 Leptin increases proliferation of human steosarcoma cells through activation of PI(3)-K and MAPK pathways. 2006 Nov 1
15 15334656 Leptin inhibits lysophosphatidic acid-induced intracellular calcium rise by a protein kinase C-dependent mechanism. 2004 Nov 1
16 12411472 Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands. 2002 Nov 2
17 10698206 Regulation of the Na,K-pump by leptin in 3T3-L1 fibroblasts. 2000 Mar 2
18 11053255 Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. 2000 Nov 1