Calcium

Rap guanine nucleotide exchange factor 3 ; Homo sapiens







17 Article(s)
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1 32890866 Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts. 2021 Jan 1
2 26704387 The signaling module cAMP/Epac/Rap1/PLCε/IP3 mobilizes acrosomal calcium during sperm exocytosis. 2016 Apr 2
3 26941424 Cyclic AMP Sensor EPAC Proteins and Their Role in Cardiovascular Function and Disease. 2016 Mar 4 1
4 27277757 Epac1 knockdown inhibits the proliferation of ovarian cancer cells by inactivating AKT/Cyclin D1/CDK4 pathway in vitro and in vivo. 2016 Jul 2
5 25609177 The proteins of exocytosis: lessons from the sperm model. 2015 Feb 1 1
6 26181635 Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLCε and to Activate p44/42 MAPK in Human Aortic Endothelial Cells. 2015 1
7 26481027 [Molecular determinants of pathological cardiac remodeling: the examples of Epac and Carabin]. 2015 Oct 2
8 25159528 Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis. 2014 Aug 27 1
9 22167199 Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells. 2012 Feb 3 1
10 22662198 Identification and function of exchange proteins activated directly by cyclic AMP (Epac) in mammalian spermatozoa. 2012 1
11 21281309 Stimulation of bursting in pre-Bötzinger neurons by Epac through calcium release and modulation of TRPM4 and K-ATP channels. 2011 Apr 1
12 19855995 Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology. 2010 Mar 1
13 20576488 Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway. 2010 Oct 1
14 19546222 Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis. 2009 Sep 11 3
15 18176800 Epac: effectors and biological functions. 2008 Jun 1
16 17276729 Epac and the cardiovascular system. 2007 Apr 1
17 16407249 Calcium-induced acrosomal exocytosis requires cAMP acting through a protein kinase A-independent, Epac-mediated pathway. 2006 Mar 31 1