RTKI cpd

epidermal growth factor receptor ; Homo sapiens







443 Article(s)
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1 35001873 RNA N6-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice. 2022 Jan 10 1
2 35228068 PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway. 2022 Apr 1
3 35628375 AG1478 Elicits a Novel Anti-Influenza Function via an EGFR-Independent, GBF1-Dependent Pathway. 2022 May 16 3
4 33481676 Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells. 2021 Aug 4
5 34093234 Protegrin-1 Regulates Porcine Granulosa Cell Proliferation via the EGFR-ERK1/2/p38 Signaling Pathway in vitro. 2021 1
6 34399098 Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains. 2021 Oct 8 1
7 34571396 G protein-coupled estrogen receptor signaling dependent epidermal growth-like factor expression is required for NPR2 inhibition and meiotic resumption in goat oocytes. 2021 Dec 1
8 34599931 Chronic arsenic increases cell migration in BEAS-2B cells by increasing cell speed, cell persistence, and cell protrusion length. 2021 Nov 1 2
9 34837677 EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2. 2021 Oct 1
10 31312936 Stimulation of neuroendocrine differentiation in prostate cancer cells by GHRH and its blockade by GHRH antagonists. 2020 Jun 1
11 31907582 Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway. 2020 May 3
12 32056244 Downregulation of CLDN6 inhibits cell proliferation, migration, and invasion via regulating EGFR/AKT/mTOR signalling pathway in hepatocellular carcinoma. 2020 Jul 1
13 32125625 Activation of Protein Kinase Cδ Contributes to the Induction of Src/EGF Receptor/ERK Signaling in Ammonia-treated Astrocytes. 2020 Jul 1
14 32219645 EGFR inhibitor AG1478 blocks the formation of 3D structures mainly through ERK signaling pathway in Matrigel-induced 3D reconstruction of eccrine sweat gland-like structures. 2020 Apr 2
15 32742490 Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer. 2020 2
16 32910506 Normal vitreous promotes angiogenesi via the epidermal growth factor receptor. 2020 Nov 1
17 30611736 Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptor. 2019 Mar 1
18 30720056 Partial agonistic effect of cetuximab on epidermal growth factor receptor and Src kinase activation in triple‑negative breast cancer cell lines. 2019 Apr 1
19 31062668 M2-like tumor-associated macrophages-secreted EGF promotes epithelial ovarian cancer metastasis via activating EGFR-ERK signaling and suppressing lncRNA LIMT expression. 2019 2
20 31615015 Ligand-Independent EGFR Activation by Anchorage-Stimulated Src Promotes Cancer Cell Proliferation and Cetuximab Resistance via ErbB3 Phosphorylation. 2019 Oct 14 1
21 31695561 Ginsenoside Rg1 activates ligand-independent estrogenic effects via rapid estrogen receptor signaling pathway. 2019 Oct 2
22 31730867 The α1-adrenoceptor-mediated human hyperplastic prostate cells proliferation is impaired by EGF receptor inhibition. 2019 Dec 15 2
23 29091309 Epiregulin (EREG) is upregulated through an IL-1β autocrine loop in Caco-2 epithelial cells with reduced CFTR function. 2018 Mar 2
24 29184982 D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR. 2018 May 2
25 29279286 EGFR transactivation is involved in TNF-α-induced expression of thymic stromal lymphopoietin in human keratinocyte cell line. 2018 Mar 1
26 29360846 The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. 2018 1
27 29589623 Nanoparticle-cell interactions induced apoptosis: a case study with nanoconjugated epidermal growth factor. 2018 Apr 5 2
28 30029165 Matrix metalloproteinase-2-induced epidermal growth factor receptor transactivation impairs redox balance in vascular smooth muscle cells and facilitates vascular contraction. 2018 Sep 2
29 27513608 The role of RNase 7 in innate cutaneous defense against Pseudomonas aeruginosa. 2017 Mar 1
30 27702388 Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16. 2017 Jan 15 2
31 28102288 Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation. 2017 Jan 19 2
32 28134774 Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma. 2017 Jan 26 2
33 28356980 Regulation of cell migration via the EGFR signaling pathway in oral squamous cell carcinoma cells. 2017 Feb 1
34 28440510 Migration of oral squamous cell carcinoma cells are induced by HGF/c-Met signalling via lamellipodia and filopodia formation. 2017 Jun 1
35 28521408 High expression of EGFR predicts poor survival in patients with resected T3 stage gastric adenocarcinoma and promotes cancer cell survival. 2017 May 1
36 28669945 [Role of epidermal growth factor receptor in house dust mite-induced airway epithelial barrier dysfunction]. 2017 Jun 20 1
37 28791638 Activation of Endosome-Associated Inert EGF Receptor Following Internalization. 2017 1
38 28811223 Influence and mechanism of 5-aminolevulinic acid-photodynamic therapy on the metastasis of esophageal carcinoma. 2017 Dec 2
39 28974440 Hijiki and sodium arsenite stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation. 2017 Dec 2
40 29163047 Biphasic Regulation of Caveolin-1 Gene Expression by Fluoxetine in Astrocytes: Opposite Effects of PI3K/AKT and MAPK/ERK Signaling Pathways on c-fos. 2017 2
41 29203120 Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation. 2017 Dec 20 1
42 26443721 The P2RY2 Receptor Induces Carcinoma Cell Migration and EMT Through Cross-Talk With Epidermal Growth Factor Receptor. 2016 Apr 4
43 26505315 Diquafosol promotes corneal epithelial healing via intracellular calcium-mediated ERK activation. 2016 Feb 1
44 26774845 Taiwan cobra cardiotoxin III suppresses EGF/EGFR-mediated epithelial-to-mesenchymal transition and invasion of human breast cancer MDA-MB-231 cells. 2016 Mar 1 1
45 26915319 Inhibitory effect of luteolin on the proliferation of human breast cancer cell lines induced by epidermal growth factor. 2016 Feb 25 2
46 27129169 Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells. 2016 May 17 1
47 27480860 Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα. 2016 Oct 2
48 27607135 Targeting H19 by lentivirus-mediated RNA interference increases A549 cell migration and invasion. 2016 Sep 1
49 27739029 HCRP1 is downregulated in non-small cell lung cancer and regulates proliferation, invasion, and drug resistance. 2016 Oct 13 1
50 23765435 Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells. 2015 Feb 2