Paclitaxel

epidermal growth factor receptor ; Homo sapiens







111 Article(s)
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1 35144131 Targeted delivery of cancer drug paclitaxel to chordomas tumor cells via an RNA nanoparticle harboring an EGFR aptamer. 2022 Apr 1
2 35372004 Efficacy and Safety of Low-Dose Nab-Paclitaxel Plus Tislelizumab in Elderly Patients With Previously Treated Metastatic Non-Small Cell Lung Cancer. 2022 1
3 35597872 Targeting epidermal growth factor receptor in paclitaxel-resistant human breast and lung cancer cells with upregulated glucose-6-phosphate dehydrogenase. 2022 May 21 7
4 33183015 A heavily pre-treated adenocarcinoma patient with EGFR exon 20 insertion mutation responded to pembrolizumab plus nab-paclitaxel/bevacizumab: a case report. 2021 Jun 1
5 33235314 Adding cetuximab to paclitaxel and carboplatin for first-line treatment of carcinoma of unknown primary (CUP): results of the Phase 2 AIO trial PACET-CUP. 2021 Feb 2
6 33721913 Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma. 2021 Sep 3
7 34023418 GABRP sustains the stemness of triple-negative breast cancer cells through EGFR signaling. 2021 Aug 28 1
8 34026617 Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers. 2021 1
9 34046939 CircMYBL2 regulates the resistance of cervical cancer cells to paclitaxel via miR-665-dependent regulation of EGFR. 2021 Dec 4
10 34256895 Identifying prognostic factors associated with overall survival in second-line paclitaxel plus ramucirumab treated human epidermal growth factor receptor 2-negative advanced/recurrent gastric cancer. 2021 Jul 1 1
11 34479917 Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. 2021 Sep-Oct 5
12 31856423 Harnessing the Potential Synergistic Interplay Between Photosensitizer Dark Toxicity and Chemotherapy. 2020 May 1
13 32083171 Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. 2020 Feb 4
14 32440910 EGFR Targeted Paclitaxel and Piperine Co-loaded Liposomes for the Treatment of Triple Negative Breast Cancer. 2020 May 21 1
15 32683880 Long-Term Effect of Erlotinib Therapy in the Third Line of Anticancer Treatment in a Patient with Non-Small-Cell Lung Cancer - a Case Report. 2020 Spring 1
16 32720079 Correction to: EGFR Targeted Paclitaxel and Piperine Co-loaded Liposomes for the Treatment of Triple Negative Breast Cancer. 2020 Jul 27 1
17 32911509 The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M2 receptor subtype. 2020 1
18 30660004 Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel- and cetuximab-conjugated nanodiamond nanocomposite. 2019 Mar 1 10
19 30662353 Calpain-2 Enhances Non-Small Cell Lung Cancer Progression and Chemoresistance to Paclitaxel via EGFR-pAKT Pathway. 2019 2
20 31146485 In Vivo Evaluation of Dual-Targeted Nanoparticles Encapsulating Paclitaxel and Everolimus. 2019 May 29 2
21 31401198 Anti-EGFR antibody conjugated thiol chitosan-layered gold nanoshells for dual-modal imaging-guided cancer combination therapy. 2019 Oct 1
22 31477168 A randomized, controlled phase II trial of neoadjuvant ado-trastuzumab emtansine, lapatinib, and nab-paclitaxel versus trastuzumab, pertuzumab, and paclitaxel in HER2-positive breast cancer (TEAL study). 2019 Sep 2 1
23 31579626 Efficacy of Paclitaxel plus TS1 against previously treated EGFR mutated non-small cell lung cancer. 2019 1
24 31762748 The Journey of an EGFR-Mutant Lung Adenocarcinoma through Erlotinib, Osimertinib and ABCP Immunotherapy Regimens: Sensitivity and Resistance. 2019 Sep-Dec 1
25 31772161 Erlotinib overcomes paclitaxel-resistant cancer stem cells by blocking the EGFR-CREB/GRβ-IL-6 axis in MUC1-positive cervical cancer. 2019 Nov 26 2
26 29411964 Enhanced Chemotherapeutic Efficacy of Paclitaxel Nanoparticles Co-delivered with MicroRNA-7 by Inhibiting Paclitaxel-Induced EGFR/ERK pathway Activation for Ovarian Cancer Therapy. 2018 Mar 7 8
27 29874151 Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo. 2018 May 2
28 29909520 Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer. 2018 Sep 1
29 30061586 Trastuzumab and paclitaxel in patients with EGFR mutated NSCLC that express HER2 after progression on EGFR TKI treatment. 2018 Aug 5
30 30254439 Lipid insertion enables targeted functionalization of paclitaxel-loaded erythrocyte membrane nanosystem by tumor-penetrating bispecific recombinant protein. 2018 4
31 30307008 Anti-EGFR lipid micellar nanoparticles co-encapsulating quantum dots and paclitaxel for tumor-targeted theranosis. 2018 Nov 7 3
32 30388386 Enhancement of radiotherapeutic efficacy for esophageal cancer by paclitaxel-loaded red blood cell membrane nanoparticles modified by the recombinant protein anti-EGFR-iRGD. 2018 Nov 3
33 30408068 Anti-EGFR anchored paclitaxel loaded PLGA nanoparticles for the treatment of triple negative breast cancer. In-vitro and in-vivo anticancer activities. 2018 7
34 27435393 Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder. 2017 Jan 15 1
35 28212993 Efficacy according to blind independent central review: Post-hoc analyses from the phase III, randomized, multicenter, IPASS study of first-line gefitinib versus carboplatin/paclitaxel in Asian patients with EGFR mutation-positive advanced NSCLC. 2017 Feb 1
36 28253574 [Reverse of the resistance to paclitaxel of the heparin binding-epidermal growth factor-like growth factor inhibitor in ovarian cancer]. 2017 Feb 25 4
37 28538405 Marked response to nab-paclitaxel in EGFR mutated lung neuroendocrine carcinoma: A case report. 2017 May 1
38 28852020 Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition. 2017 Aug 29 2
39 31305693 Erratum: Marked response to nab-paclitaxel in EGFR mutated lung neuroendocrine carcinoma: A case report: Erratum. 2017 Jul 1
40 26338546 Cost-effectiveness analysis of EGFR mutation testing in patients with non-small cell lung cancer (NSCLC) with gefitinib or carboplatin-paclitaxel. 2016 Sep 2
41 26709987 Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors. 2016 Mar 15 1
42 26799187 p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells. 2016 Feb 16 5
43 27100344 Anticancer activity of drug conjugates in head and neck cancer cells. 2016 Jun 1 1
44 24670093 EGFR-targeted poly(ethylene glycol)-distearoylphosphatidylethanolamine micelle loaded with paclitaxel for laryngeal cancer: preparation, characterization and in vitro evaluation. 2015 2
45 25370413 In vitro synergistic antitumor efficacy of sequentially combined chemotherapy/icotinib in non‑small cell lung cancer cell lines. 2015 Jan 3
46 25553650 A phase 2 study of bevacizumab in combination with carboplatin and paclitaxel in patients with non-squamous non-small-cell lung cancer harboring mutations of epidermal growth factor receptor (EGFR) after failing first-line EGFR-tyrosine kinase inhibitors (HANSHIN Oncology Group 0109). 2015 Feb 1
47 25583261 BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. 2015 Jan 13 1
48 25684511 Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel. 2015 1
49 25998561 A tumor-penetrating recombinant protein anti-EGFR-iRGD enhance efficacy of paclitaxel in 3D multicellular spheroids and gastric cancer in vivo. 2015 Sep 18 2
50 26622855 Paclitaxel induces apoptosis and reduces proliferation by targeting epidermal growth factor receptor signaling pathway in oral cavity squamous cell carcinoma. 2015 Oct 2