Cyclosporine

peptidylprolyl isomerase F ; Homo sapiens







48 Article(s)
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1 34953947 Targeting mitochondrial permeability transition pore ameliorates PM2.5-induced mitochondrial dysfunction in airway epithelial cells. 2022 Feb 15 4
2 33495413 Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis. 2021 Jan 20 1
3 33538721 One-bead-one-compound screening approach to the identification of cyclic peptoid inhibitors of cyclophilin D as neuroprotective agents from mitochondrial dysfunction. 2021 Mar 7 3
4 32187393 T-2 toxin cytotoxicity mediated by directly perturbing mitochondria in human gastric epithelium GES-1 cells. 2020 Aug 2
5 32339494 Targeting putative components of the mitochondrial permeability transition pore for novel therapeutics. 2020 Jul 1
6 32454060 Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection. 2020 Jul 1
7 33046783 Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC1/2 and cyclophilin D-dependent manner via the ANT-associated pore. 2020 Oct 12 5
8 30291799 OSCP subunit of mitochondrial ATP synthase: role in regulation of enzyme function and of its transition to a pore. 2019 Nov 1
9 31500337 Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening. 2019 Sep 7 4
10 31884421 Targeting cyclophilin-D by miR-1281 protects human macrophages from Mycobacterium tuberculosis-induced programmed necrosis and apoptosis. 2019 Dec 28 1
11 29426003 Programmed necrosis in heart disease: Molecular mechanisms and clinical implications. 2018 Mar 2
12 27664163 Prevention of Cyclophilin D-Mediated mPTP Opening Using Cyclosporine-A Alleviates the Elevation of Necroptosis, Autophagy and Apoptosis-Related Markers Following Global Cerebral Ischemia-Reperfusion. 2017 Jan 3
13 27993675 The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells. 2017 Jan 29 1
14 28363167 Emodin targets mitochondrial cyclophilin D to induce apoptosis in HepG2 cells. 2017 Jun 4
15 28784775 Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase. 2017 Aug 22 1
16 26679998 Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis. 2016 Feb 26 1
17 26775841 Targeting colorectal cancer cells by a novel sphingosine kinase 1 inhibitor PF-543. 2016 Feb 12 1
18 26936128 mTOR signaling pathway is inhibited downstream of the cyclophilin D-mediated mitochondrial permeability transition in honokiol-triggered regulated necrosis. 2016 Apr 2
19 25179911 The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury. 2015 Jan 1
20 25576381 C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: a mechanism study. 2015 Mar 1 2
21 26004138 Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells. 2015 Sep 2
22 26024660 ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis. 2015 May 30 1
23 26170095 Modelling the molecular mechanism of protein-protein interactions and their inhibition: CypD-p53 case study. 2015 Nov 3
24 26356268 Spongionella Secondary Metabolites Regulate Store Operated Calcium Entry Modulating Mitochondrial Functioning in SH-SY5Y Neuroblastoma Cells. 2015 2
25 24291231 Hypoxic preconditioning-induced mitochondrial protection is not disrupted in a cell model of mtDNA T8993G mutation-induced F1F0-ATP synthase defect: the role of mitochondrial permeability transition. 2014 Feb 1
26 24603333 Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury. 2014 Mar 6 7
27 24732633 Gemcitabine-induced pancreatic cancer cell death is associated with MST1/cyclophilin D mitochondrial complexation. 2014 Aug 2
28 24735534 Curcumin-induced melanoma cell death is associated with mitochondrial permeability transition pore (mPTP) opening. 2014 May 23 2
29 24946211 Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells. 2014 Jul 18 2
30 23322110 Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axis. 2013 Apr 1
31 23525116 Cyclophilin D modulates cell death transition from early apoptosis to programmed necrosis induced by honokiol. 2013 May 2
32 23845906 Cisplatin-induced non-apoptotic death of pancreatic cancer cells requires mitochondrial cyclophilin-D-p53 signaling. 2013 Aug 9 2
33 22892127 Ultra-violet B (UVB)-induced skin cell death occurs through a cyclophilin D intrinsic signaling pathway. 2012 Sep 7 2
34 20026006 Cyclophilin D in mitochondrial pathophysiology. 2010 Jun-Jul 1
35 20577812 Synergistic induction of apoptosis and caspase-independent autophagic cell death by a combination of nitroxide Tempo and heat shock in human leukemia U937 cells. 2010 Oct 1
36 20658967 A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection. 2010 Aug 1
37 19168026 The role of the mitochondrial permeability transition pore in heart disease. 2009 Nov 2
38 19509316 Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases. 2009 Sep 1
39 18191430 Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A. 2008 Mar 15 2
40 15573402 Mitochondrial permeability transition in CNS trauma: cause or effect of neuronal cell death? 2005 Jan 1-15 1
41 16167169 Genetic dissection of the permeability transition pore. 2005 Jun 2
42 12871122 Cyclophilin D as a drug target. 2003 Aug 1
43 12022946 The permeability transition pore complex: another view. 2002 Feb-Mar 2
44 10574961 Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans. 1999 Dec 3 1
45 9714750 Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. 1998 Aug 10 2
46 9820802 Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition. 1998 Dec 1 5
47 9309684 Two modes of activation of the permeability transition pore: the role of mitochondrial cyclophilin. 1997 Sep 3
48 1346997 Characterization of the cytochrome P-450 gene family responsible for the N-dealkylation of the ergot alkaloid CQA 206-291 in humans. 1992 Jan-Feb 1