Organophosphates

acetylcholinesterase ; Rattus norvegicus







76 Article(s)
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1 35583269 Efficiency of the removal of tetraethyl pyrophosphate (TEPP) pesticide in water: use of cork granules as a natural adsorbent on acetylcholinesterase activity in neuronal PC12 cell. 2022 May 18 2
2 33497710 In vitro age-related differences in rats to organophosphates. 2021 Apr 6
3 33540058 Potential role of a newly AChE reactivator in the depressive-like behavior induced by malathion. 2021 Apr 1 1
4 33545185 Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study. 2021 Apr 2
5 33682265 Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression. 2021 Jun 2
6 31158460 Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX. 2020 Jan 1
7 31694074 Pre-clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion-induced toxicity. 2020 Apr 4
8 31933077 Protective effects of thymoquinone and diallyl sulphide against malathion-induced toxicity in rats. 2020 Apr 2
9 32319115 Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates. 2020 Nov 4
10 32436233 Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18 F]-VXS. 2020 Nov 2
11 33031921 A single dose of the organophosphate triazophos induces fear extinction deficits accompanied by hippocampal acetylcholinesterase inhibition. 2020 Nov - Dec 1
12 30458229 Atropine counteracts the depressive-like behaviour elicited by acute exposure to commercial chlorpyrifos in rats. 2019 Jan - Feb 2
13 31408696 Ocular surface histopathological insult following sarin and VX exposure and potential treatments in the rat model. 2019 Oct 10 1
14 30345360 Prevention of pesticide-induced neuronal dysfunction and mortality with nucleophilic poly-Oxime topical gel. 2018 Oct 2
15 30496567 Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain. 2018 Dec 1 1
16 27129421 Novel bifunctional hybrid small molecule scavengers for mitigating nerve agents toxicity. 2016 Nov 25 2
17 27177985 Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor. 2016 Jul 2
18 28959576 Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon. 2016 2
19 25082528 Combined in silico and in vivo studies shed insights into the acute acetylcholinesterase response in rat and human brain. 2015 May-Jun 1
20 24291005 Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression. 2014 Jan 5
21 24716794 A novel fluorine-18 β-fluoroethoxy organophosphate positron emission tomography imaging tracer targeted to central nervous system acetylcholinesterase. 2014 Jul 16 2
22 21717485 Pharmacokinetic study of two acetylcholinesterase reactivators, trimedoxime and newly synthesized oxime K027, in rat plasma. 2013 Jan 2
23 23123249 Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates. 2013 Mar 25 2
24 22285544 Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain. 2012 Mar 3
25 22608349 Effect of Calea serrata Less. n-hexane extract on acetylcholinesterase of larvae ticks and brain Wistar rats. 2012 Oct 26 2
26 23244429 Acetylcholinesterase inhibitors as pretreatment before acute exposure to organophosphates: assessment using methyl-paraoxon. 2012 Dec 1
27 23373324 [Paraoxonase activity and lipid peroxides concentration in serum of rats subchronically intoxicated with chlorpyrifos--organophosphate insecticide]. 2012 2
28 21237238 Esterase metabolism of cholinesterase inhibitors using rat liver in vitro. 2011 Mar 15 2
29 21419823 Lipid peroxidation, oxidative stress and acetylcholinesterase in rat brain exposed to organophosphate and pyrethroid insecticides. 2011 Jun 1
30 21748880 [Liver and serum glutathione concentration and liver hydrogen peroxide in rats subchronically intoxicated with chlorfenvinphos--organophosphate insecticide]. 2011 2
31 19899158 Enantioselective interaction with acetylcholinesterase of an organophosphate insecticide fenamiphos. 2010 Jun 1
32 20498005 Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate. 2010 Aug 1
33 19728005 Time-course changes of acetylcholinesterase activity in blood and some tissues in rats after intoxication by Russian VX. 2009 Nov 2
34 18324340 Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection. 2008 2
35 18579126 An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents. 2008 Sep 25 1
36 21783883 Evaluation of nicotinic receptors agonists and antagonists against paraoxon exposed PC12 cells. 2008 Jul 2
37 21791372 Protective effects of mecamylamine and atropine against α(4)β(2) nicotinic receptor expression and functional toxicity in paraoxon-treated rats. 2008 Sep 2
38 17366821 Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon. 2007 Jan 3
39 19858641 The effect of chronic consumption of paraoxon on basal and pentagastrin-stimulated gastric acid and pepsin secretion in rats. 2007 Oct-Dec 2
40 16289123 Muscarinic modulations of neuronal anticholinesterase responses. 2005 Dec 15 2
41 16601802 A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun. 2005 Dec 1
42 21783514 Plasma acetylcholinesterase as a biomarker of triazophos neurotoxicity in young and adult rats. 2005 May 2
43 14691213 Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. 2004 Mar 2
44 15342957 Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides. 2004 Dec 2
45 15591769 Methyl parathion increases neuronal activities in the rat locus coeruleus. 2004 Nov-Dec 1
46 15639788 Reactivation of organophosphate-inhibited acetylcholinesterase by quaternary pyridinium aldoximes. 2004 1
47 12478623 Effects of chronic dermal exposure to nonlethal doses of methyl parathion on brain regional acetylcholinesterase and muscarinic cholinergic receptors in female rats. 2003 Jan 1 1
48 12505439 Influence of malathion pretreatment on the toxicity of anilofos in male rats: a biochemical interaction study. 2003 Mar 14 2
49 12893843 Cholinesterase reactivation in vivo with a novel bis-oxime optimized by computer-aided design. 2003 Oct 1
50 12201035 Behavioural responsiveness to amphetamine or scopolamine following repeated exposure to chlorphenvinphos in rats. 2002 4