| 1 |
33540058 | Potential role of a newly AChE reactivator in the depressive-like behavior induced by malathion. | 2021 Apr 1 |
2 |
| 2 |
33545185 | Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study. | 2021 Apr |
3 |
| 3 |
31158460 | Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX. | 2020 Jan |
1 |
| 4 |
31694074 | Pre-clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion-induced toxicity. | 2020 Apr |
1 |
| 5 |
32319115 | Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates. | 2020 Nov |
3 |
| 6 |
32436233 | Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18 F]-VXS. | 2020 Nov |
4 |
| 7 |
32502538 | Antidepressant-like effect of (3Z)-5-Chloro-3-(hydroxyimino)indolin-2-one in rats exposed to malathion: Involvement of BDNF-Trkβ pathway and AChE. | 2020 Sep 1 |
1 |
| 8 |
29722548 | In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators. | 2019 Jul |
2 |
| 9 |
29098328 | Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain. | 2018 Feb |
1 |
| 10 |
29482737 | Kinetic analysis of oxime-assisted reactivation of human, Guinea pig, and rat acetylcholinesterase inhibited by the organophosphorus pesticide metabolite phorate oxon (PHO). | 2018 Feb |
1 |
| 11 |
30176331 | Efficacy of antidotes and their combinations in the treatment of acute carbamate poisoning in rats. | 2018 Sep 1 |
1 |
| 12 |
28696367 | The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203. | 2017 Jul 11 |
4 |
| 13 |
29091431 | Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase. | 2017 Nov 22 |
2 |
| 14 |
27129421 | Novel bifunctional hybrid small molecule scavengers for mitigating nerve agents toxicity. | 2016 Nov 25 |
1 |
| 15 |
27177985 | Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor. | 2016 Jul |
3 |
| 16 |
25461321 | Discovery of non-oxime reactivators using an in silico pharmacophore model of reactivators for DFP-inhibited acetylcholinesterase. | 2015 Jan 27 |
2 |
| 17 |
25894563 | A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice. | 2015 Mar |
2 |
| 18 |
22901042 | The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice. | 2013 Feb |
1 |
| 19 |
23123249 | Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates. | 2013 Mar 25 |
6 |
| 20 |
23422169 | An acetylcholinesterase-inspired biomimetic toxicity sensor. | 2013 May |
3 |
| 21 |
22696932 | The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice. | 2012 |
2 |
| 22 |
20569082 | Changes of rat plasma total low molecular weight antioxidant level after tabun exposure and consequent treatment by acetylcholinesterase reactivators. | 2011 Feb |
1 |
| 23 |
21954536 | Biochemical insight into soman intoxication and treatment with atropine, HI-6, trimedoxime, and K203 in a rat model. | 2011 |
1 |
| 24 |
19746406 | The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice. | 2010 Mar |
4 |
| 25 |
20167212 | Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo. | 2010 Sep 6 |
2 |
| 26 |
18686075 | An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice. | 2009 Jan |
1 |
| 27 |
19338015 | Effect of five acetylcholinesterase reactivators on tabun-intoxicated rats: induction of oxidative stress versus reactivation efficacy. | 2009 Aug |
1 |
| 28 |
19552519 | A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice. | 2009 Aug |
1 |
| 29 |
19603416 | Minireview: does in-vitro testing of oximes help predict their in-vivo action after paraoxon exposure? | 2009 Aug |
2 |
| 30 |
17964625 | Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS. | 2008 Feb 15 |
2 |
| 31 |
18547554 | A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats. | 2008 Sep 25 |
4 |
| 32 |
18608751 | A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium compounds (K206, K269) with currently available oximes against tabun in rats and mice. | 2008 Dec |
2 |
| 33 |
18991751 | Pyridinium oxime reactivators of cholinesterase inhibited by diisopropyl-fluorophosphate (DFP): predictive value of in-vitro testing for in-vivo efficacy. | 2008 Nov |
5 |
| 34 |
17674811 | A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats. | 2007 Jun |
3 |
| 35 |
16766478 | In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase. | 2006 Aug |
1 |
| 36 |
16952906 | A comparison of the efficacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods. | 2006 Oct |
5 |
| 37 |
17265677 | Substituted monoquaternary oximes as reactivators of cyclosarin--and chlorpyrifos--inhibited acetylcholinesterase. | 2006 Dec |
2 |
| 38 |
15901095 | A comparison of the potency of newly developed oximes (K005, K027, K033, K048) and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited rat brain acetylcholinesterase by in vitro methods. | 2005 Apr 23 |
3 |
| 39 |
16025528 | In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions. | 2005 Jul-Aug |
1 |
| 40 |
16170392 | New quaternary pyridine aldoximes as casual antidotes against nerve agents intoxications. | 2005 Jun |
2 |
| 41 |
16259317 | A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods. | 2005 |
5 |
| 42 |
16393932 | Bispyridinium oximes as antidotal treatment of cyclosarin poisoning-in vitro and in vivo testing. | 2005 Nov-Dec |
1 |
| 43 |
16601802 | A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun. | 2005 Dec |
3 |
| 44 |
15033007 | [Protective effect of memantine on N-methyl-D-aspartate receptor in dichlorvos-poisoned rat brain]. | 2004 Feb |
2 |
| 45 |
15171567 | Oximes-induced reactivation of rat brain acetylcholinesterase inhibited by VX agent. | 2004 Apr |
1 |
| 46 |
15446359 | In vitro reactivation of acetylcholinesterase inhibited by cyclosarin using bisquaternary pyridinium aldoximes K005, K033, K027 AND K048. | 2004 |
1 |
| 47 |
12893843 | Cholinesterase reactivation in vivo with a novel bis-oxime optimized by computer-aided design. | 2003 Oct |
3 |
| 48 |
15008517 | A comparison of the ability of a new bispyridinium oxime--1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods. | 2003 Dec |
1 |
| 49 |
10566233 | [Comparison of the reactivating effect of BI-6, a new asymmetrical bispyridinium oxime, with oxime HI-6 and obidoxime on soman-inhibited acetylcholinesterase in the diaphragm and various parts of the brain in rats]. | 1999 Aug 30 |
1 |
| 50 |
9543466 | Preclinical pharmacology of metrifonate. | 1998 Mar-Apr |
1 |