Decitabine

cyclin dependent kinase inhibitor 2B ; Homo sapiens







23 Article(s)
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1 30651784 Elevated methylation of cyclin dependent kinase inhibitor 2B contributes to the risk of coronary heart disease in women. 2019 Jan 1
2 29070127 [Inhibitory Effect of Decitabine on Proliferation of MDS-L Cells and Its Mechanism]. 2017 Oct 1
3 25652099 Downregulation of HO-1 promoted apoptosis induced by decitabine via increasing p15INK4B promoter demethylation in myelodysplastic syndrome. 2015 Apr 5
4 26317501 Targeting the Sonic Hedgehog-Gli1 Pathway as a Potential New Therapeutic Strategy for Myelodysplastic Syndromes. 2015 1
5 26782424 Role of heme oxygenase-1 in demethylating effects on SKM-1 cells induced by decitabine. 2015 Dec 22 3
6 24519046 [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells]. 2014 Jan 1
7 23683424 [p15(INK4B) methylation on prognosis and response to decitabine in patients with MDS]. 2013 Mar 4
8 22399596 Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. 2012 Mar 2
9 22654424 Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells. 2012 May 21 1
10 21125401 Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. 2011 Jun 2
11 19881540 Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. 2010 Jan 28 4
12 20051228 CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus. 2010 Feb 5 1
13 20190193 Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML. 2010 Apr 15 2
14 18704418 Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15INK4b gene methylation and high global DNA methylation. 2009 Mar 1
15 18718068 [Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. 2008 Aug 4
16 17258075 Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. 2007 Feb 1
17 16292549 In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies. 2005 Dec 2
18 15015578 Activation of expression of p15, p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine). 2004 Jan-Feb 3
19 12351408 Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. 2002 Oct 15 6
20 12485524 [The re-expression of p15(INK4B) gene in leukemia cells induced by in vitro DNA methyltransferase and histone deacetylase inhibition]. 2002 Nov 2
21 11479232 Tumor suppressor genes in the 9p21 gene cluster are selective targets of inactivation in neuroendocrine gastroenteropancreatic tumors. 2001 Aug 1 2
22 11602627 Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development. 2001 Oct 1
23 8631003 Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. 1996 Feb 15 1