Etoposide

ATM serine/threonine kinase ; Homo sapiens







37 Article(s)
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1 35231830 Discovery of novel ataxia telangiectasia mutated (ATM) kinase modulators: Computational simulation, biological evaluation and cancer combinational chemotherapy study. 2022 Apr 5 3
2 35604590 Alternative end-joining originates stable chromosome aberrations induced by etoposide during targeted inhibition of DNA-PKcs in ATM-deficient tumor cells. 2022 May 23 2
3 34960710 ATM-Dependent Phosphorylation of Hepatitis B Core Protein in Response to Genotoxic Stress. 2021 Dec 5 4
4 33257565 HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement. 2020 Dec 15 1
5 30943920 Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells. 2019 Apr 3 2
6 29759113 Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations. 2018 May 8 2
7 29759988 Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics. 2018 Aug 1
8 28195382 Contribution of ATM and ATR kinase pathways to p53-mediated response in etoposide and methyl methanesulfonate induced DNA damage. 2017 Mar 1
9 28387728 Microvesicles Contribute to the Bystander Effect of DNA Damage. 2017 Apr 7 5
10 28928376 Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression. 2017 Sep 19 3
11 26986476 PTEN enhances G2/M arrest in etoposide-treated MCF‑7 cells through activation of the ATM pathway. 2016 May 4
12 25088203 BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. 2015 Jun 4 9
13 25821946 Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line. 2015 Mar 30 1
14 26556501 Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos. 2015 1
15 24953561 Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells. 2014 Aug 1
16 24965603 Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP). 2014 Jun 25 1
17 22960274 ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis. 2013 Jan 1 2
18 22282239 PI3K-like kinases restrain Pim gene expression in endothelial cells. 2012 Feb 1
19 22739265 Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells. 2012 Aug 1
20 23058634 Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. 2012 Nov 1 2
21 23226797 Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells. 2012 Dec 4
22 19858003 Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure. 2010 Feb 1
23 20637859 Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. 2010 Nov 4
24 21048951 ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot. 2010 Oct 27 1
25 19296337 Stress response of a p53 homologue in the radioresistant Sf9 insect cells. 2009 Mar 1
26 19488905 Cytotoxicity and mitochondrial apoptosis induced by etoposide in melanoma cells. 2009 Aug 2
27 18200038 A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL. 2008 Jul 1
28 18431490 Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. 2008 Apr 23 6
29 17297310 Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase. 2007 Feb 1 2
30 17420723 Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage. 2007 Sep 13 1
31 14872059 Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21. 2004 1
32 12767922 P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. 2003 Jun 13 1
33 12874009 G2 arrest in response to topoisomerase II inhibitors: the role of p53. 2003 Jul 15 3
34 11821415 ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. 2002 Apr 12 1
35 11096068 The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner. 2001 Feb 16 2
36 11741320 Etoposide and adriamycin but not genistein can activate the checkpoint kinase Chk2 independently of ATM/ATR. 2001 Dec 21 1
37 10533459 ATM heterozygote cells exhibit intermediate levels of apoptosis in response to streptonigrin and etoposide. 1999 Jul 1