| 1 |
35163972 | The System Profile of Renal Drug Transporters in Tubulointerstitial Fibrosis Model and Consequent Effect on Pharmacokinetics. | 2022 Jan 21 |
1 |
| 2 |
29884691 | Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates. | 2018 Sep |
1 |
| 3 |
30234099 | Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin. | 2018 |
1 |
| 4 |
28337147 | 3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing. | 2017 |
1 |
| 5 |
26702643 | The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3. | 2016 Feb 1 |
1 |
| 6 |
27019345 | Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions. | 2016 Jun 10 |
3 |
| 7 |
27324234 | Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride. | 2016 Aug |
2 |
| 8 |
27758931 | Impact of Substrate-Dependent Inhibition on Renal Organic Cation Transporters hOCT2 and hMATE1/2-K-Mediated Drug Transport and Intracellular Accumulation. | 2016 Dec |
3 |
| 9 |
24947923 | Complex disease-, gene-, and drug-drug interactions: impacts of renal function, CYP2D6 phenotype, and OCT2 activity on veliparib pharmacokinetics. | 2014 Aug 1 |
1 |
| 10 |
23034939 | Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2. | 2013 Jan 1 |
1 |
| 11 |
24040847 | Effect of cimetidine, a model drug for inhibition of the organic cation transport (OCT2/MATE1) in the kidney, on the pharmacokinetics of glycopyrronium. | 2013 Oct |
1 |
| 12 |
22072731 | Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney. | 2012 Feb |
1 |
| 13 |
20601443 | Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase. | 2010 Aug 15 |
1 |
| 14 |
19203538 | Influence of the hOCT2 inhibitor cimetidine on the cellular accumulation and cytotoxicity of oxaliplatin. | 2009 Jan |
1 |
| 15 |
17971819 | Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. | 2008 Apr |
1 |
| 16 |
11953440 | The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization. | 2002 Jun 21 |
2 |
| 17 |
12089365 | cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney. | 2002 Jul |
1 |