Doxorubicin

caspase 3 ; Mus musculus







82 Article(s)
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1 35584053 Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance. 2022 Jun 13 1
2 33357780 Alleviation of the doxorubicin-induced nephrotoxicity by fasudil in vivo and in vitro. 2021 Jan 1
3 34192626 Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer. 2021 Dec 2
4 34205942 Exercise Inhibits Doxorubicin-Induced Damage to Cardiac Vessels and Activation of Hippo/YAP-Mediated Apoptosis. 2021 Jun 1 1
5 34476531 Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer. 2021 Dec 1
6 34734816 Angiotensin receptor-neprilysin inhibition by sacubitril/valsartan attenuates doxorubicin-induced cardiotoxicity in a pretreatment mice model by interfering with oxidative stress, inflammation, and Caspase 3 apoptotic pathway. 2021 Nov 3
7 31833156 Involvement of Yes-associated protein 1 (YAP1) in doxorubicin-induced cytotoxicity in H9c2 cardiac cells. 2020 Mar 1
8 31862454 Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME. 2020 Feb 1 6
9 31877550 LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress. 2020 Mar 1
10 31918264 Cardamonin protects against doxorubicin-induced cardiotoxicity in mice by restraining oxidative stress and inflammation associated with Nrf2 signaling. 2020 Feb 1
11 32227969 Dendrimer Conjugation Enhances Tumor Penetration and Efficacy of Doxorubicin in Extracellular Matrix-Expressing 3D Lung Cancer Models. 2020 May 4 1
12 32352097 Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release. 2020 Jun 7 1
13 32352929 Resveratrol attenuates doxorubicin-induced meiotic failure through inhibiting oxidative stress and apoptosis in mouse oocytes. 2020 Apr 30 1
14 32468050 Doxorubicin and CD‑CUR inclusion complex co‑loaded in thermosensitive hydrogel PLGA‑PEG‑PLGA localized administration for osteosarcoma. 2020 Aug 1
15 32534162 Apoptosis-inducing peptide loaded in PLGA nanoparticles induces anti-tumor effects in vivo. 2020 Jul 30 1
16 32673667 Sodium thiosulfate prevents doxorubicin-induced DNA damage and apoptosis in cardiomyocytes in mice. 2020 Sep 15 1
17 32882870 Flavokawain B and Doxorubicin Work Synergistically to Impede the Propagation of Gastric Cancer Cells via ROS-Mediated Apoptosis and Autophagy Pathways. 2020 Sep 1 2
18 33149585 Efficacy of Combination Therapy with Linalool and Doxorubicin Encapsulated by Liposomes as a Two-in-One Hybrid Carrier System for Epithelial Ovarian Carcinoma. 2020 1
19 31196352 Bioinspired Drug Delivery Carrier for Enhanced Tumor-Targeting in Melanoma Mice Model. 2019 Jul 1 1
20 31347748 Caspase-3-mediated GSDME activation contributes to cisplatin- and doxorubicin-induced secondary necrosis in mouse macrophages. 2019 Sep 2
21 31437492 Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation. 2019 Oct 15 1
22 31534548 Co-delivery of glycyrrhizin and doxorubicin by alginate nanogel particles attenuates the activation of macrophage and enhances the therapeutic efficacy for hepatocellular carcinoma. 2019 1
23 31563690 Janus nanocarrier-based co-delivery of doxorubicin and berberine weakens chemotherapy-exacerbated hepatocellular carcinoma recurrence. 2019 Dec 2
24 31998130 Doxorubicin Induces Endotheliotoxicity and Mitochondrial Dysfunction via ROS/eNOS/NO Pathway. 2019 1
25 28536949 Exercise and Doxorubicin Treatment Modulate Cardiac Mitochondrial Quality Control Signaling. 2018 Feb 1
26 29907098 IP3R-Grp75-VDAC1-MCU calcium regulation axis antagonists protect podocytes from apoptosis and decrease proteinuria in an Adriamycin nephropathy rat model. 2018 Jun 15 1
27 30063064 Curcumin attenuates doxorubicin-induced cardiotoxicity via suppressing oxidative stress and preventing mitochondrial dysfunction mediated by 14-3-3γ. 2018 Aug 15 2
28 30271146 Deepened cellular/subcellular interface penetration and enhanced antitumor efficacy of cyclic peptidic ligand-decorated accelerating active targeted nanomedicines. 2018 1
29 30482226 Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer. 2018 Nov 27 1
30 30622447 Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin. 2018 Oct-Dec 2
31 28373086 Optical imaging and anticancer chemotherapy through carbon dot created hollow mesoporous silica nanoparticles. 2017 Jun 1
32 28456679 Assembly of polymer micelles through the sol-gel transition for effective cancer therapy. 2017 Jun 10 1
33 28560697 The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations. 2017 Sep 1
34 28849533 Protective Effect of Taurine on Mice with Doxorubicin-induced Acute Kidney Injury. 2017 1
35 28922986 Attenuation of doxorubicin-induced cardiotoxicity and genotoxicity by an indole-based natural compound 3,3'-diindolylmethane (DIM) through activation of Nrf2/ARE signaling pathways and inhibiting apoptosis. 2017 Oct 1
36 29110957 A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy. 2017 Sep 14 1
37 29931936 [Effects of caspase inhibitor z-VAD-fmk on the expressions of calumenin, caspase-3, GRP78 and GRP94 in adriamycin-injured cardiomyocytes]. 2017 Mar 8 2
38 26224681 PI3K Inhibitor Combined With Chemotherapy Can Enhance the Apoptosis of Neuroblastoma Cells In Vitro and In Vivo. 2016 Oct 1
39 26450947 Acute Treatment of Resveratrol Alleviates Doxorubicin-Induced Myotoxicity in Aged Skeletal Muscle Through SIRT1-Dependent Mechanisms. 2016 Jun 1
40 26980746 Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors. 2016 Apr 12 1
41 27033790 [Mechanisms for inhibitory effect of ALDH2 on doxorubicin-induced cytotoxicity in C2C12 myogenic cell line]. 2016 Mar 28 1
42 23628005 The prostaglandin agonist beraprost aggravates doxorubicin-mediated apoptosis by increasing iNOS expression in cardiomyocytes. 2015 1
43 25505252 Induced phenotype targeted therapy: radiation-induced apoptosis-targeted chemotherapy. 2015 Feb 3
44 25657296 Noninvasive molecular imaging of apoptosis in a mouse model of anthracycline-induced cardiotoxicity. 2015 Feb 2
45 25680506 Theanine prevents doxorubicin-induced acute hepatotoxicity by reducing intrinsic apoptotic response. 2015 Apr 3
46 25742619 Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling. 2015 1
47 26276089 Effect of metformin and adriamycin on transplantable tumor model. 2015 Oct 1
48 26722406 Effects of PPARα/PGC-1α on the energy metabolism remodeling and apoptosis in the doxorubicin induced mice cardiomyocytes in vitro. 2015 1
49 24117488 Protective effect of a direct renin inhibitor in acute murine model of cardiotoxicity and nephrotoxicity. 2014 Oct 1
50 24326424 Desacyl ghrelin prevents doxorubicin-induced myocardial fibrosis and apoptosis via the GHSR-independent pathway. 2014 Feb 1