Irinotecan

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







13 Article(s)
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Title
Pub. Year
#Total Relationships
1 22379477 Irinotecan-induced dysarthria. 2012 Jan 2
2 19663821 Irinotecan side effects relieved by the use of HI-6 oxime: in vivo experimental approach. 2009 Dec 2
3 17516995 Irinotecan toxicity to human blood cells in vitro: relationship between various biomarkers. 2007 Jun 3
4 17713603 Evaluation of HI-6 oxime: potential use in protection of human acetylcholinesterase inhibited by antineoplastic drug irinotecan and its cyto/genotoxicity in vitro. 2007 2
5 15772291 The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. 2005 Jun 7
6 16257398 Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11. 2005 Dec 15 2
7 15536465 Inhibition of acetylcholinesterase in patients receiving irinotecan (camptothecin-11). 2004 Nov 2
8 11956509 Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role. 2002 Apr 6
9 12049482 The inhibition of acetylcholinesterase by irinotecan and related camptothecins: key structural properties and experimental variables. 2001 Aug-Oct 4
10 10197614 The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase. 1999 Apr 1 6
11 10416605 Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts. 1999 Jul 15 1
12 10570064 The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). 1999 Dec 2
13 9726096 Gastrointestinal toxicity or irinotecan. 1998 Aug 2