Polyamines

spermine oxidase ; Homo sapiens







43 Article(s)
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1 35452470 Development and characterization of rabbit monoclonal antibodies that recognize human spermine oxidase and application to immunohistochemistry of human cancer tissues. 2022 2
2 34522028 The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme. 2021 Sep 14 2
3 32350444 Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling. 2020 May 1
4 33173604 Identification of a Novel Substrate-Derived Spermine Oxidase Inhibitor. 2020 Jul-Sep 4
5 31159606 Discovery and antitumor evaluation of novel inhibitors of spermine oxidase. 2019 Dec 3
6 31561575 Polyamine Catabolism in Acute Kidney Injury. 2019 Sep 26 2
7 29729200 Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features. 2018 Oct 2
8 30006473 Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators. 2018 Aug 31 2
9 28017891 Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. 2017 Jan 28 2
10 28423064 Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047. 2017 2
11 29093526 Spermine oxidase promotes bile canalicular lumen formation through acrolein production. 2017 Nov 1 1
12 27433286 The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBPβ rather than Enterotoxigenic Bacteroides fragilis Infection. 2016 1
13 25153488 Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer. 2015 Feb 2 2
14 23771789 Polyamine catabolism in carcinogenesis: potential targets for chemotherapy and chemoprevention. 2014 Mar 1
15 24190492 Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells. 2014 Jan 2
16 24854736 The Glu²¹⁶/Ser²¹⁸ pocket is a major determinant of spermine oxidase substrate specificity. 2014 Aug 1 2
17 23449327 Pentamines as substrate for human spermine oxidase. 2013 1
18 23828398 Structure-function relationships in the evolutionary framework of spermine oxidase. 2013 Jun 1
19 23892915 Inhibition of polyamine oxidase prevented cyclin-dependent kinase inhibitor-induced apoptosis in HCT 116 colon carcinoma cells. 2013 Dec 2
20 24009852 Polyamines and their metabolites as diagnostic markers of human diseases. 2013 Jan 2
21 21809080 Spermine oxidase: ten years after. 2012 Feb 6
22 22294330 Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells. 2012 Apr 2
23 23021806 A mass spectrometric method to determine activities of enzymes involved in polyamine catabolism. 2012 Oct 20 1
24 20839014 Probing mammalian spermine oxidase enzyme-substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization. 2011 Apr 2
25 21318873 A simple assay for mammalian spermine oxidase: a polyamine catabolic enzyme implicated in drug response and disease. 2011 3
26 20059804 Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers. 2010 Jul 2
27 20127992 Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity. 2010 Sep 2
28 19685053 The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer. 2009 Dec 2
29 18302221 Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues. 2008 May 15 3
30 18422650 Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology. 2008 Jun 6
31 17371265 Inflammation and polyamine catabolism: the good, the bad and the ugly. 2007 Apr 2
32 16428315 Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both? 2006 Jan 2
33 16519678 Inhibition of polyamine and spermine oxidases by polyamine analogues. 2006 Mar 4
34 15496143 Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein. 2005 Mar 15 2
35 15791459 Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity. 2005 Jul 6
36 16207710 Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. 2005 Dec 2 1
37 15290341 Inhibitors of polyamine metabolism: review article. 2004 Jul 4
38 15574757 Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis. 2004 Dec 1 1
39 12477380 Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. 2003 Feb 15 1
40 12653639 The role of polyamine catabolism in anti-tumour drug response. 2003 Apr 5
41 12727196 Properties of purified recombinant human polyamine oxidase, PAOh1/SMO. 2003 May 16 1
42 12827295 Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells. 2003 Nov 6
43 12398765 Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics. 2002 Dec 15 4