| 1 |
34344987 | Targeting leukemia-specific dependence on the de novo purine synthesis pathway. | 2022 Feb |
2 |
| 2 |
35285625 | Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of 13C-Bicarbonate Incorporation. | 2022 Apr 5 |
2 |
| 3 |
33596246 | Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer. | 2021 |
1 |
| 4 |
32344379 | Nwd1 Regulates Neuronal Differentiation and Migration through Purinosome Formation in the Developing Cerebral Cortex. | 2020 May 22 |
1 |
| 5 |
32422575 | PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression. | 2020 Jul |
3 |
| 6 |
32571877 | Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target. | 2020 Aug 14 |
2 |
| 7 |
32632107 | PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2. | 2020 Jul 6 |
1 |
| 8 |
30641222 | Roles of highly expressed PAICS in lung adenocarcinoma. | 2019 Apr 15 |
2 |
| 9 |
31600779 | PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome. | 2019 Nov 15 |
2 |
| 10 |
31624245 | Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy. | 2019 Oct 17 |
2 |
| 11 |
29744932 | Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer. | 2018 Jun |
1 |
| 12 |
30097015 | Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines. | 2018 Aug 10 |
1 |
| 13 |
28411283 | Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer. | 2017 Mar 15 |
1 |
| 14 |
27527091 | Serum activities of adenosine deaminase, dipeptidyl peptidase IV and prolyl endopeptidase in patients with fibromyalgia: diagnostic implications. | 2016 Oct |
1 |
| 15 |
26140362 | Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer. | 2015 Sep 15 |
2 |
| 16 |
23553965 | Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 Å resolution. | 2013 Aug |
1 |
| 17 |
23717670 | A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes. | 2013 |
1 |
| 18 |
17224163 | Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis. | 2007 Mar 9 |
4 |
| 19 |
15566465 | Mapping of the bovine genes of the de novo AMP synthesis pathway. | 2004 Dec |
1 |
| 20 |
10413613 | Molecular analysis of the Cryptococcus neoformans ADE2 gene, a selectable marker for transformation and gene disruption. | 1999 Jun |
1 |
| 21 |
9108165 | Role of NRF-1 in bidirectional transcription of the human GPAT-AIRC purine biosynthesis locus. | 1997 May 1 |
1 |
| 22 |
7923143 | Identification of genes overexpressed in tumors through preferential expression screening in trophoblasts. | 1994 Oct 1 |
1 |
| 23 |
8336716 | Coexpression of two closely linked avian genes for purine nucleotide synthesis from a bidirectional promoter. | 1993 Aug |
1 |
| 24 |
2004782 | Mapping of a locus correcting lack of phosphoribosylaminoimidazole carboxylase activity in Chinese hamster ovary cell Ade-D mutants to human chromosome 4. | 1991 Feb |
1 |
| 25 |
2253271 | Cloning and sequencing of a human cDNA coding for a multifunctional polypeptide of the purine pathway by complementation of the ade2-101 mutant in Saccharomyces cerevisiae. | 1990 Nov |
1 |